An update on epilepsy

Schoenberg, Mike R.; Frontera, Alfred T.; Bozorg, Ali; Hernandez-Frau, Pedro E.; Vale, Fernando Ĺ.; Benbadis, Selim R.

doi:10.1586/ern.11.50

Cited by 5 publications

(4 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…13,21 Although the patient burden has increased dramatically, corresponding medical and surgical modalities of treatment have not yielded adequate results in decreased morbidity for patients, especially for epileptic patients who did not achieve disease control through surgical intervention. 14,16,18,19,22 The increase in prevalence described above has also been coupled with an overall increase in admission for epilepsy, as well as an increasing national health care bill as described by Bodenheimer.…”

Section: Discussionmentioning

confidence: 99%

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

Vivas¹,

Baaj²,

Benbadis

et al. 2012

FOC

View full text Add to dashboard Cite

Object The aim of this study was to analyze the national health care burden of patients diagnosed with epilepsy in the US and to analyze any changes in the length of stay, mean charges, in-hospital deaths (mortality), and disposition at discharge. Methods A retrospective review of the Nationwide Inpatient Sample (NIS) database for epilepsy admissions was completed for the years from 1993 to 2008. The NIS is maintained by the Agency for Healthcare Research and Quality and represents a 20% random stratified sample of all discharges from nonfederal hospitals within the US. Patients with epilepsy were identified using ICD-9 codes beginning with 345.XX. Approximately 1.1 million hospital admissions were identified over a span of 15 years. Results Over this 15-year period (between 1993 and 2008), the average hospital charge per admission for patients with epilepsy has increased significantly (p < 0.001) from $10,050 to $23,909, an increase of 137.9%. This is in spite of a 33% decrease in average length of stay from 5.9 days to 3.9 days. There has been a decrease in the percentage of in-hospital deaths by 57.9% and an increase in discharge to outside medical institutions. Conclusions The total national charges associated with epilepsy in 2008 were in excess of $2.7 billion (US dollars, normalized). During the studied period, the cost per day for patients rose from $1703.39 to $6130.51. In spite of this drastic increase in health care cost to the patient, medical and surgical treatment for epilepsy has not changed significantly, and epilepsy remains a major source of morbidity.

show abstract

Section: Discussionmentioning

confidence: 99%

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

Vivas¹,

Baaj²,

Benbadis

et al. 2012

FOC

View full text Add to dashboard Cite

show abstract

“…Therefore, the capacity of educational systems to prepare learners for complex twentyfirst century life and work is under increasing scrutiny. The importance of this point is emphasized by research showing significant interconnections between educational achievements, occupational success and well-being (e.g., Samuel et al, 2013). In 2017, The European Commission affirmed the need to strengthen European identity through education and culture, foregrounding the responsibility of educational systems for students' development of the necessary tools to thrive in the new paradigm of a knowledge society.…”

Section: Introductionmentioning

confidence: 99%

Remembering, Reflecting, Reframing: Examining Students’ Long-Term Perceptions of an Innovative Model for University Teaching

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Crises originating from the back of the parietal lobe are most often clinically silent until they spread in the primary sensitive cortex or on other lobes, including frontal, temporal, or occipital (first of all, the temporal region and motor frontal supplementary region) (10). Somatic-sensitive disorder appears on the contralateral side of the seizure origin (11), but in some cases it can also occur on the same side (12). …”

Section: Introductionmentioning

confidence: 99%

Accuracy of Conventional Diagnostic Methods for Identifying Structural Changes in Patients with Focal Epilepsy

et al. 2016

View full text Add to dashboard Cite

Background:Epilepsy is a neurological disorder characterized by abnormal firing of nerve impulses in the brain.Aim:This study aims to investigate the frequency of appearance of pathological changes in conventional examination methods (electroencephalography–EEG, brain computerized tomography -CT or brain magnetic resonance imaging – MRI) in patients with epilepsy, and relationship between clinical manifestations and localization of changes in CT or MRI.Methods:In this study we have included 110 patients with focal epilepsy who fulfilled the inclusion criteria out of 557 initially diagnosed patients. Detailed clinical examination together with brain imaging (CT and MRI) and electroencephalography examination was performed. We have evaluated the accuracy of each diagnostic method to localize the epileptic focus. Diagnosis of epilepsy was determined by the ILAE (International League Against Epilepsy) criteria of the year 1989, and classification of epileptic seizures was made according to the ILAE classification 2010.Results:Electroencephalography presented changes in 60.9% of patients; brain CT in 42.1%, and MRI in 78% of the patients. The results of our study showed that clinical manifestations were not always conveyed with pathological changes in conventional examining methods performed. Of the total of 79 patients with changes in imaging (8 with changes in CT and 71 in MRI), 79.7% presented a clinical picture compatible with the region in which morphological changes were found, while in 20.3% of patients the presented morphological changes were not aligned with the clinical picture.Conclusion:In patients with epilepsy, conventional examination methods do not always find pathological changes, while clinical manifestations of epilepsy did not always coincide with the location of changes in imaging. Further studies are needed to see if there is clear border between focal and generalized epilepsy.

show abstract

An update on epilepsy

Cited by 5 publications

References 23 publications

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

Remembering, Reflecting, Reframing: Examining Students’ Long-Term Perceptions of an Innovative Model for University Teaching

Accuracy of Conventional Diagnostic Methods for Identifying Structural Changes in Patients with Focal Epilepsy

Contact Info

Product

Resources

About