An X-ray powder diffraction study ofcis-dichloridobis(2-methyl-2H-tetrazol-5-amine-κN⁴)platinum(II), a tetrazole-containing analogue of cisplatin

Abstract

The structure of the title compound, cis-[PtCl(2)(C(2)H(5)N(5))(2)], was analysed using in-house X-ray powder diffraction data at room temperature. The structure was solved by direct methods and refined using Rietveld analysis. A slightly distorted square-planar coordination geometry is formed around the Pt atom by two Cl atoms and two ring N atoms of the 2-methyl-2H-tetrazol-5-amine ligands, which are in a cis configuration. The planes of the tetrazole rings are inclined at 79.7 (7) and 73.8 (6)° with respect to the coordination plane, with their substituents oriented in such a way that the complex as a whole has approximate C(2) symmetry. Intermolecular N-H···Cl hydrogen bonds mediate the formation of a three-dimensional supramolecular network.

Water‐Soluble Platinum(II) Complexes Featuring 2‐Alkyl‐2H‐tetrazol‐5‐ylacetic Acids: Synthesis, Characterization, and Antiproliferative Activity

“…Among platinum(II) complexes featuring neutral N‐substituted tetrazoles, complexes of cis geometry are significantly less studied than their trans congeners. For example, only cis ‐[PtCl 2 (5‐amino‐2‐methyltetrazole) 2 ] has been structurally characterized to date with use of powder X‐ray diffraction . Therefore, compounds 4 and 5· 2H 2 O are the first cis ‐isomeric complexes of this type whose structures have been elucidated by single‐crystal X‐ray diffraction.…”

Structure elucidation of 3-[1-(6-methoxy-2-naphtyl)ethyl]-6-(2,4-dichlorophenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine, C23H18Cl2N4OS from synchrotron X-ray powder diffraction

“…At the first step, the sigma values, defining the weights of restraints, were set to 0.05°for the bond angles and 0.005 Å for the bond lengths. At the second step, the sigma values were set to 0.1°and 0.01 Å for the bond angles and bond lengths, respectively (Ivashkevich et al, 2011). At the beginning of the refinement of atomic positions, the coordinates of the Cl atoms were refined.…”

5‐Amino‐2‐isopropenyltetrazole and its Cupric Chloride Complex: Synthesis, Structure and Magnetism

“…Only coordination compounds of 5‐amino‐2‐methyltetrazole and 5‐amino‐2‐ tert ‐butyltetrazole have been prepared and characterized by X‐ray analysis. In particular, silver perchlorate, [12] copper(II) chloride and bromide, [13] copper(II) chlorate, [14] bromate, [15] perchlorate [16] and platinum(II) chloride [17] complexes with 5‐amino‐2‐methyltetrazole have been reported. For 5‐amino‐2‐ tert ‐butyltetrazole, only copper(II), platinum(II) and palladium(II) chloride complexes have been characterized [18] …”