Anaemia, a common but often unrecognized risk in diabetic patients: A review

Angelousi, A.; Larger, Étienne

doi:10.1016/j.diabet.2014.06.001

Cited by 77 publications

(66 citation statements)

References 98 publications

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“…In our cohort, neither creatinine nor albumin level predicted anemia. Although diabetic nephropathy, renal insufficiency and macroalbuminuria are associated with anemia in diabetic patients [18,20], an increased risk for anemia is also observed in diabetics with normal renal function, consistent with our findings [17,[21][22][23].…”

Section: Discussionsupporting

confidence: 92%

Predicting the emergence of anemia — A large cohort study

Gafter‐Gvili

Cohen

Avni

et al. 2015

European Journal of Internal Medicine

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Section: Discussionsupporting

confidence: 92%

Predicting the emergence of anemia — A large cohort study

Gafter‐Gvili

Cohen

Avni

et al. 2015

European Journal of Internal Medicine

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“…Thus, diabetes, as well as hyperglycemia due to its nature, is also an inflammatory disease character. Studies show that the longer the duration of the disease and/ or loss of glycemic control, the higher the inflammatory process [21].…”

Section: Discussionmentioning

confidence: 99%

Exploring the Interrelationship Between Electrolytes, Anemia, and Glycosylated Hemoglobin (Hba1c) Levels in Type 2 Diabetics

Rajagopal

Ganesan

Abdullah

et al. 2018

Asian J Pharm Clin Res

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Objective: The aim of this study is to analyze the interrelationship and pattern of electrolyte imbalance and compare the correlation between serum electrolytes, glycosylated hemoglobin (HbA1C), and hemoglobin (Hb) levels between Type 2 diabetic patients and non-diabetic subjects. Methods:This study was conducted in 300 subjects (150 diabetics and 150 non-diabetics) and further categorized as anemic and non-anemic within each group. Blood samples were analyzed for HbA1C, hemoglobin, and serum electrolyte levels.Results: Sodium (Na + ) levels in diabetics were significantly lower and potassium (K + ) as well as chloride (Cl − ) levels were significantly higher, when compared with non-diabetics. A significant positive correlation between HbA1C and potassium as well as chloride levels in contrast to negative correlation with sodium levels was observed in both genders. Among diabetics with anemia, we found significantly lower sodium and higher potassium and chloride. Conclusion:In diabetics, levels of sodium were significantly lower, and potassium as well as chloride was significantly higher when compared with non-diabetics. Our study clearly demonstrates an association between electrolytes, hemoglobin, and HbA1C levels in diabetes. This insight should pave the way for pathophysiology-directed therapy, thus contributing to the avoidance of several deleterious effects associated with electrolyte disorders and their treatment.

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“…Normocytic, normochromic anaemia is also seen in acute blood loss, anaemia of chronic disease, aplastic anaemia (bone marrow failure), drug therapy and haemolytic anaemia, among others. Of these, the two most common causes are chronic disease and drug therapy (Opasich et al, 2005;Angelousi and Larger, 2014).…”

Section: Discussionmentioning

confidence: 99%