Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Balbino, Marcos; Silva, Gisele Rodrigues da; G, Corrêia

doi:10.1590/s1679-45082012000300021

Cited by 17 publications

(1 citation statement)

References 10 publications

(16 reference statements)

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“…Additionally, IVFA is limited in its image quality and resolution of the fine foveal vasculature, 30 , 33 – 35 can obscure capillary details secondary to dye leakage, 36 , 37 and is an invasive procedure that is associated with a variety of side effects. 38 – 40 …”

Section: Introductionmentioning

confidence: 99%

Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

Krawitz

Phillips

Bavier

et al. 2018

Trans. Vis. Sci. Tech.

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PurposeTo describe a new technique for mapping parafoveal intercapillary areas (PICAs) using optical coherence tomography angiography (OCTA), and demonstrate its utility for quantifying parafoveal nonperfusion in diabetic retinopathy (DR).MethodsNineteen controls, 15 diabetics with no retinopathy (noDR), 15 with nonproliferative diabetic retinopathy (NPDR), and 15 with proliferative diabetic retinopathy (PDR) were imaged with 10 macular OCTA scans. PICAs were automatically delineated on the averaged superficial OCTA images. Following creation of an eccentricity-specific reference database from the controls, all PICAs greater than 2 SD above the reference means for PICA area and minor axis length were identified as nonperfused areas. Regions of interest (ROI) at 300 μm and 1000 μm from the foveal avascular zone (FAZ) margin were analyzed. Percent nonperfused area was defined as summed nonperfused areas divided by ROI area. Values were compared using Kruskal-Wallis and post-hoc Mann-Whitney U tests.ResultsMedian values for total percent nonperfused area at the 300-μm ROI were 2.09, 2.44, 18.08, and 27.55 in the control, noDR, NPDR, and PDR groups, respectively. Median values at the 1000-μm ROI were 3.10, 3.31, 13.42, and 23.00. While there were no significant differences between the control and noDR groups, significant differences were observed between all other groups at both ROIs.ConclusionsPercent nonperfused area can quantify parafoveal nonperfusion in DR and can be calculated through automatic delineation of PICAs in an eccentricity-specific manner using a standard deviation mapping approach.Translational RelevancePercent nonperfused area shows promise as a metric to measure disease severity in diabetic retinopathy.

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Section: Introductionmentioning

confidence: 99%

Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

Krawitz

Phillips

Bavier

et al. 2018

Trans. Vis. Sci. Tech.

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Anaphylaxis caused by intravenous fluorescein: clinical characteristics and review of literature

Kim

Sohn

et al. 2013

Intern Emerg Med

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Anaphylaxis is a severe, potentially fatal, systemic allergic reaction that suddenly occurs after contact with an allergy-causing substance. The aims of this study were to evaluate the clinical characteristics and outcomes of patients who were diagnosed with anaphylaxis to fluorescein. The medical records of patients with anaphylaxis to intravenous fluorescein angiography (IVFA) admitted to the emergency department between January 2010 and June 2012 were retrospectively reviewed. Among 12,005 times of IVFA, a total of 10 patients (0.083 %) were included in this study. The mean age was 58.3 years, and 50.0 % were men. The most common presentation was hypotension (systolic blood pressure <90 mmHg) (70 %) followed by nausea and vomiting (60 %). Especially, patients with diabetes were more prone to develop hypotension and most hypotensive events occurred in less than 3 min. All of our patients recovered without sequelae and mortality following prompt and proper intervention. Although the incidence is low, anaphylaxis due to intravenous fluorescein can occur during IVFA. Physicians should be aware of this possible complication, and be prepared to treat it.

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Fluorescein

2014

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Anafilaxia com convulsões após angiografia com fluoresceína em paciente ambulatorial

Cited by 17 publications

References 10 publications

Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

Parafoveal Nonperfusion Analysis in Diabetic Retinopathy Using Optical Coherence Tomography Angiography

Anaphylaxis caused by intravenous fluorescein: clinical characteristics and review of literature

Fluorescein

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