Análisis demográfico de una clínica de cardiopatías congénitas del Instituto Mexicano del Seguro Social, con interés en el adulto

Márquez-González, Horacio; Yáñez-Gutiérrez, Lucelli; Rivera-May, Jimena Lucely; López-Gallegos, Diana; Almeida-Gutiérrez, Eduardo

doi:10.1016/j.acmx.2017.09.003

Cited by 4 publications

(3 citation statements)

References 17 publications

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“…VSD is the third most common isolated defect, after patent ductus arteriosus (PDA) and inter-atrial communication (IAC) [ 17 ]. Some studies have reported a prevalence of children under 6 years of age with VSD of between 9.3 and 10.29% in Mexico [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

González-Peña

Calvo-Anguiano

Martínez-de-Villarreal

et al. 2021

Nutrients

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Background: DNA methylation is the best epigenetic mechanism for explaining the interactions between nutrients and genes involved in intrauterine growth and development programming. A possible contributor of methylation abnormalities to congenital heart disease is the folate methylation regulatory pathway; however, the mechanisms and methylation patterns of VSD-associated genes are not fully understood. Objective: To determine if maternal dietary intake of folic acid (FA) is related to the methylation status (MS) of VSD-associated genes (AXIN1, MTHFR, TBX1, and TBX20). Methods: Prospective case–control study; 48 mothers and their children were evaluated. The mothers’ dietary variables were collected through a food frequency questionnaire focusing on FA and the consumption of supplements with FA. The MS of promoters of genes was determined in the children. Results: The intake of FA supplements was significantly higher in the control mothers. In terms of maternal folic acid consumption, significant differences were found in the first trimester of pregnancy. Significant differences were observed in the MS of MTHFR and AXIN1 genes in VSD and control children. A correlation between maternal FA supplementation and MS of AXIN1 and TBX20 genes was found in control and VSD children, respectively. Conclusions: A lower MS of AXIN1 genes and a higher MS of TBX20 genes is associated with FA maternal supplementation.

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Section: Introductionmentioning

confidence: 99%

Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

González-Peña

Calvo-Anguiano

Martínez-de-Villarreal

et al. 2021

Nutrients

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“…Several studies have reported an increasing prevalence of congenital heart diseases in Mexico, with variations in the prevalence rates depending on the specific type of heart disease and the region of the country [14]. Genetic factors, such as consanguinity and a high prevalence of certain gene mutations, may contribute to the increased prevalence of congenital heart diseases in the Mexican population [15]. Environmental factors, including maternal use of medications during pregnancy, exposure to infections, and poor prenatal care, may also play a role [16].…”

Section: Discussionmentioning

confidence: 99%

Predictors of ICU Admission in Children with COVID-19: Analysis of a Large Mexican Population Dataset

Cárdenas-Rojas

Guzmán-Esquivel

Murillo-Zamora

2023

JCM

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Children, although mostly affected mildly or asymptomatically, have also developed severe coronavirus disease 2019 (COVID-19). This study aims to assess potential predictors of intensive care unit (ICU) admission in a large population (n = 21,121) of children aged 0–9 years with laboratory-confirmed disease. We performed a cross-sectional analysis of a publicly available dataset derived from the normative epidemiological surveillance of COVID-19 in Mexico. The primary binary outcome of interest was admission to the ICU due to respiratory failure. Results showed that immunosuppressed children and those with a personal history of cardiovascular disease had a higher likelihood of being admitted to the ICU, while increasing age and the pandemic duration were associated with a lower likelihood of admission. The study’s results have the potential to inform clinical decision-making and enhance management and outcomes for children affected by COVID-19 in Mexico.

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“…nacimientos al año, estimamos alrededor de 20,000 niños con enfermedad cardiaca congénita, lo que hace a estas patologías un problema de salud importante. 2 La presentación de cardiopatías congénitas en gemelos al parecer no es tan común y el abordaje de la lesión y el pronóstico tienen relación con la edad gestacional y el peso al nacer. 3 www.medigraphic.com/actamedica www.medigraphic.org.mx…”

Section: Introductionunclassified

Reparación de cardiopatía congénita crítica en el prematuro

Realpe¹,

Aguilar²,

Darszon³

et al. 2021

Acta Médica Grupo Ángeles

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Síganos en Twitter: @actaMHA INTRODUCCIÓNLos defectos cardiacos son las malformaciones más frecuentes al nacimiento, se estima a nivel mundial una incidencia de 10-12 niños por cada 1,000 nacidos vivos. 1 Esto implica que, si en nuestro país hay un poco más de 2 millones de Reparación de cardiopatía congénita crítica en el prematuroRepair of critical congenital heart disease in prematurity

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Análisis demográfico de una clínica de cardiopatías congénitas del Instituto Mexicano del Seguro Social, con interés en el adulto

Abstract: CHD is a late diagnosis; it is necessary to create a national register to promote new health policies and a rational distribution of resources for these patients.

Cited by 4 publications

References 17 publications

Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

Predictors of ICU Admission in Children with COVID-19: Analysis of a Large Mexican Population Dataset

Reparación de cardiopatía congénita crítica en el prematuro

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