Gross Regional Domestic Product (GRDP) is a reflection of a region's economic growth. West Nusa Tenggara (NTB) is one of the provinces that contributes to good GRDP for Indonesia. The purpose of this research is to modeling GRDP in NTB using spatial econmetrics. The data used is the GRDP data of each district / city in NTB Province as a response variable and factors that affect the number of workers, capital value and electrification ratio as predictor variables. The results showed that there is a spatial dependence on the district / city GRDP in NTB Province on the error model so that the model formed is the Spatial Error Model (SEM) with a rho of 71.1% and an AIC value of 173.34.