Health education is part of discharge planning, an important intervention in enabling patients able to continue their self-care at home. The purpose of this study was to determine the difference of the level of knowledge and skills of perioperative patients in self-care when health education was carried out, between in the team nursing care method with the primary nursing method. The research design used a descriptive correlation method, measurements were made using a knowledge questionnaire and for skills using an observation sheet. Analysis with dependent sample t-test and independent sample t-test, the places of research are in the Demang Sepulau Raya Hospital and in A. Dadi Tjokrodipo, Hospital in Lampung, 2019. The results show, after using the primary nursing method, there is a significant increase the knowledge and skills of patients and their families and health education can be carried out more often. In conclusion, health education is very important, especially if it is integrated into the primary nursing method. It is recommended that this method be continued with the existence of supporting instruments, procedures for health education, commitment of the staff and improving skills of nurses in providing health education.