Analysing spectral changes over time to identify articulatory impairments in dysarthria

Slis, Anneke; Lévêque, Nathalie; Fougeron, Cécile; Assal, Frédéric; Lancia, Leonardo

doi:10.1121/10.0003332

Cited by 4 publications

(1 citation statement)

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“…In their study, speed was calculated based on the mean slope of the second formant, which may not be linearly related to actual articulatory speed and may explain discrepancies between our findings for speed and theirs. It may also explain why another acoustic study showed events in the spatial domain to be more sensitive than durational measures in differentiating mild ALS and PD [ 45 ].…”

Section: Discussionmentioning

confidence: 99%

Articulatory Performance in Dysarthria: Using a Data-Driven Approach to Estimate Articulatory Demands and Deficits

Kuruvilla-Dugdale

Mefferd

2022

Brain Sciences

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This study pursued two goals: (1) to establish range of motion (ROM) demand tiers (i.e., low, moderate, high) specific to the jaw (J), lower lip (LL), posterior tongue (PT), and anterior tongue (AT) for multisyllabic words based on the articulatory performance of neurotypical talkers and (2) to identify demand- and disease-specific articulatory performance characteristics in talkers with amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). J, LL, PT, and AT movements of 12 talkers with ALS, 12 talkers with PD, and 12 controls were recorded using electromagnetic articulography. Vertical ROM, average speed, and movement duration were measured. Results showed that in talkers with PD, J and LL ROM were already significantly reduced at the lowest tier whereas PT and AT ROM were only significantly reduced at moderate and high tiers. In talkers with ALS, J ROM was significantly reduced at the moderate tier whereas LL, PT, and AT ROM were only significantly reduced at the highest tier. In both clinical groups, significantly reduced J and LL speeds could already be observed at the lowest tier whereas significantly reduced AT speeds could only be observed at the highest tier. PT speeds were already significantly reduced at the lowest tier in the ALS group but not until the moderate tier in the PD group. Finally, movement duration, but not ROM or speed performance, differentiated between ALS and PD even at the lowest tier. Results suggest that articulatory deficits vary with stimuli-specific motor demands across articulators and clinical groups.

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Section: Discussionmentioning

confidence: 99%

Articulatory Performance in Dysarthria: Using a Data-Driven Approach to Estimate Articulatory Demands and Deficits

Kuruvilla-Dugdale

Mefferd

2022

Brain Sciences

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Speakers coarticulate less in response to both real and imagined communicative challenges: An acoustic analysis of the LUCID corpus

Guo

Smiljanić

2023

Journal of Phonetics

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Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases

Lévêque

Slis

Lancia

et al. 2022

J Speech Lang Hear Res

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Purpose: This study aims to investigate acoustic change over time as biomarkers to differentiate among spastic–flaccid dysarthria associated with amyotrophic lateral sclerosis (ALS), spastic dysarthria associated with primary lateral sclerosis (PLS), flaccid dysarthria associated with spinal and bulbar muscular atrophy (SBMA), and to explore how these acoustic parameters are affected by dysarthria severity. Method: Thirty-three ALS patients with mixed flaccid–spastic dysarthria, 17 PLS patients with pure spastic dysarthria, 18 SBMA patients with pure flaccid dysarthria, and 70 controls, all French speakers, were included in the study. Speakers produced vowel–glide sequences targeting different vocal tract shape changes. The mean and coefficient of variation of the total squared change of mel frequency cepstral coefficients were used to capture the degree and variability of acoustic changes linked to vocal tract modifications over time. Differences in duration of acoustic events were also measured. Results: All pathological groups showed significantly less acoustic change compared to controls, reflecting less acoustic contrast in sequences. Spastic and mixed spastic–flaccid dysarthric speakers showed smaller acoustic changes and slower sequence production compared to flaccid dysarthria. For dysarthria subtypes associated with a spastic component, reduced degree of acoustic change was also associated with dysarthria severity. Conclusions: The acoustic parameters partially differentiated among the dysarthria subtypes in relation to motor neuron diseases. While similar acoustic patterns were found in spastic–flaccid and spastic dysarthria, crucial differences were found between these two subtypes relating to variability. The acoustic patterns were much more variable in ALS. This method forms a promising clinical tool as a diagnostic marker of articulatory impairment, even at mild stage of dysarthria progression in all subtypes.

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Analysing spectral changes over time to identify articulatory impairments in dysarthria

Cited by 4 publications

References 50 publications

Articulatory Performance in Dysarthria: Using a Data-Driven Approach to Estimate Articulatory Demands and Deficits

Articulatory Performance in Dysarthria: Using a Data-Driven Approach to Estimate Articulatory Demands and Deficits

Speakers coarticulate less in response to both real and imagined communicative challenges: An acoustic analysis of the LUCID corpus

Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases

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