Globally, wildfires are considered the most commonly occurring disasters, resulting from natural and anthropogenic ignition sources. Wildfires consist of burning standing biomass at erratic degrees of intensity, severity, and frequency. Consequently, wildfires generate large amounts of smoke and other toxic pollutants that have devastating impacts on ambient air quality and human health. There is, therefore, a need for a comprehensive study that characterizes land-atmosphere interactions with regard to wildfires, critical for understanding the interrelated and multidimensional impacts of wildfires. Current studies have a limited scope and a narrow focus, usually only focusing on one aspect of wildfire impacts, such as air quality without simultaneously considering the impacts on land surface changes and vice versa. In this study, we use several multisource data to determine the spatial distribution, frequency, disturbance characteristics of and variability and distribution of pollutants emitted by wildfires. The specific objectives were to (1) study the sources of wildfires and the period they are prevalent in sub-Saharan Africa over a 9 year period, i.e., 2007-2016, (2) estimate the seasonal disturbance of wildfires on various vegetation types, (3) determine the spatial distribution of black carbon (BC), carbon monoxide (CO) and smoke, and (4) determine the vertical height distribution of smoke. The results show largest burned areas in December-January-February (DJF), June-July-August (JJA) and September-October-November (SON) seasons, and reciprocal high emissions of BC, CO, and smoke, as observed by Modern-Era Retrospective Analysis for Research and Applications version 2 (MERRA-2) and Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO). In addition, the results reveal an increasing trend in the magnitude of BC, and CO concentration driven by meteorological conditions such as low precipitation, low relative humidity, and low latent heat flux. Overall, this study demonstrates the value of multisource remotely sensed data in characterising long-term wildfire patterns and associated emissions. The results in this study are critical for informing better regional fire management and air quality control strategies to preserve endangered species and habitats, promote sustainable land management, and reduce greenhouse gases (GHG) emissions.