Analysis of central corneal thickness in black Cameroonian children

Eballe, André Omgbwa; Epée, Emilienne; Koki, Godefroy; Bella, Assumpta Lucienne

doi:10.2147/opto.s14214

Cited by 6 publications

(4 citation statements)

References 19 publications

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“…The average lag-time (from onset of symptoms to initiation of treatment) was 9.27 months with a maximum of 36 months. The lag time in the study was much higher 17,18 than that reported in several studies. However, in a study done in Tanzania, the mean lag time was 10 months 19 which was slightly higher than that attained in the study.…”

Section: Lag-timecontrasting

confidence: 58%

Modes of presentation, management and outcome of retinoblastoma treatment at University Teaching Hospital

Nyaywa,

Mutati,

Chintu

2016

mjz

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Objectives: To establish the presentation, management and short-term outcomes of retinoblastoma treatment at UTH from January 2006- December 2012. treatment outcomes 6 months after initiation of treatment at The statistical analyses were performed using the statistical package SPSS version 20. Method: This was a retrospective case series study of the modes of presentation, management of retinoblastoma and UTH from January 2006- December 2012. The data was collected from registers for the eye unit inpatient and outpatient, histopathology laboratory, pediatric oncology department as well as patients' files. The data collected included demographics, clinical presentation, histopathology reports, treatment modalities, and treatment outcome at 6 months after initiation of treatment. Results: There were 57 African participants in the study of which 26 (45.6%) were males and 31 (54.4%) were females. The youngest was 0.75 months old while the oldest was 132 month old. The average age of the participants was 31.1 months old (with a standard deviation of 21.96). The average time lag from the onset of symptoms to treatment at UTH was 9.27 months with a minimum of one month and a maximum of 36 months. 71.2% had unilateral retinoblastoma, 28.8% had bilateral retinoblastoma however no trilateral retinoblastoma was observed. The most common presentations were proptosis (47.3%), leukocoria (36.8%), phthisis bulbi (4%), hyphema (2%), orbital cellulitis (1%) and uveitis (1%). The common treatment regimens were enucleation and chemotherapy (28.8%), exenteration and chemotherapy (15%), enucleation, chemotherapy and radiotherapy (3.4%). Moreover, 8.5% had enucleation only whilst 3.4% had exenteration, chemotherapy and radiotherapy treatment regimen. In the study, the treatment outcomes 6 months post initiation of treatment were abandoned treatment 17.5%, while 49.2% died and 33.3% were alive. Conclusion: The common presentation was proptosis (47.3%) and leukocoria (36.8%). The most common treatment outcome was death, alive followed by abandonment treatment. Treatment was completed in 22% of the participants. Delay in diagnosis of retinoblastoma remains a challenge as seen in the study by the high mean lag time and late presentation. The diagnosis of retinoblastoma from the referral centers was accurate in 50 % of the patients. Awareness of retinoblastoma to primary health care givers and parents will help to improve early referrals. Further, we recommend the integration of knowledge of retinoblastoma into the curriculum of primary health care giver to facilitate quick referral of patient.

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Section: Lag-timecontrasting

confidence: 58%

Modes of presentation, management and outcome of retinoblastoma treatment at University Teaching Hospital

Nyaywa,

Mutati,

Chintu

2016

mjz

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“…35.9µm were reported in Sudan (Mohamed et al, 2009) and Cameroon (Eballe et al, 2010) respectively. Eballe and co-workers chose to work with CCT values just between 527 and 560µm, thereby excluding a lot of values outside this range and possibly explains the lower average value documented in their study (Eballe et al, 2010).…”

Section: Discussionmentioning

confidence: 87%

“…Eballe and co-workers chose to work with CCT values just between 527 and 560µm, thereby excluding a lot of values outside this range and possibly explains the lower average value documented in their study (Eballe et al, 2010). This shows that the variation in CCT values among blacks of African descent goes beyond boundaries of race.…”

Section: Discussionmentioning

confidence: 88%

“…Other studies have confirmed that the relationship between CCT and IOP in normal subjects demonstrated a positive linear correlation (Iyamu and Ituah 2008;Sahin et al, 2008;Mohamed et al, 2009;Eballe et al, 2010). Kotecha (2005) claimed that CCT alone cannot account for all the variation in measured IOP amongst individuals, and it is likely that complex corneal biomechanical properties have an important influence on IOP measurement.…”

Section: Discussionmentioning

confidence: 89%

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The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

Iyamu¹,

Kio²,

Idu³

et al. 2011

Sierra Leone j. biomed. res.

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The aim of this study was to investigate the relationship between central corneal thickness (CCT) and intraocular pressure (IOP) in a predominantly black population. A total of eighty-five subjects (right eyes) with mean age 44.7 ± 15.1 years consisting of 49 males and 36 females were recruited for this study. The central corneal thickness was measured by ultrasound pachymetry (SW-1000P pachymeter, Tianjin Suowei Electronic Technology, China) and intraocular pressure with Keeler Pulsair EasyEye Non-contact tonometer (Keeler Instruments, USA). The mean CCT for the studied population was 550.0 ± 36.3µm, while the mean IOP was 15.0 ± 2.6mmHg. Although there was a downward trend in the central corneal thickness towards the older age, the association between CCT and age was significant (r=-0.25, p=0.021). However, the association between intraocular pressure and age was not significant (r=0.091, p=0.41). There was no significant association between CCT and IOP (r=0.052, p=0.64). Neither central corneal thickness nor intraocular pressure was influenced by age. There was no significant association between central corneal thickness and intraocular pressure.

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Central corneal thickness in southern Egypt

Mostafa

2013

Int Ophthalmol

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The study aimed to determine mean central corneal thickness (CCT) in a southern Egyptian population according to gender and age using ultrasonic pachymetry and to compare these CCT measurements to different populations. A prospective, observational, consecutive case series of 4,368 non-glaucomatous subjects (emmetropes and myopes) aged 16-70 years was carried out from August 2010 to March 2013 at the outpatient ophthalmology clinic in Sohag University Hospital and the Laser Vision Center in Sohag City, Egypt. Refraction, keratometry, slit-lamp examination, and intraocular pressure (IOP) measurements were obtained for all subjects. CCT was measured by ultrasonic pachymetry. The average CCT was 530.06 ± 38.03 μm. Average CCT was 532.6 ± 33.3 μm in emmetropes, 531.5 ± 31.3 μm in myopes <6 diopters (D), 531.1 ± 31.4 μm in myopes >6 D and 533 ± 33 μm in hyperopes, with no statistically significant difference between the groups. There was a statistically significant difference in CCT between age groups and gender. There was a strong correlation between CCT and IOP among the non-glaucomatous population. CCT was found to be lower in Egyptians than in Caucasian, Hispanic, and Japanese populations but comparable to African and African American populations.

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Analysis of central corneal thickness in black Cameroonian children

Cited by 6 publications

References 19 publications

Modes of presentation, management and outcome of retinoblastoma treatment at University Teaching Hospital

Modes of presentation, management and outcome of retinoblastoma treatment at University Teaching Hospital

The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

Central corneal thickness in southern Egypt

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