Analysis of clinical effect and radiographic outcomes of Isobar TTL system for two-segment lumbar degenerative disease: a retrospective study

Ji, Zhisheng; Yang, Hua; Yang, Yu-Hao; Li, Shaojin; Luo, Jiankai; Zhang, Guowei; Lin, Hongsheng

doi:10.1186/s12893-020-0680-8

Cited by 14 publications

(26 citation statements)

References 26 publications

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“…A total of 201 relevant studies were obtained through a preliminary search, including 66 from PubMed, 12 from Ovid, 13 from EMBASE, 10 from Web of Science, 10 from MEDLINE, 46 from CNKI, 24 from VIP and 68 from WanFang. After eliminating duplicate studies, reading topics and abstracts and full-text re screening, 7 RCT studies [ 8 – 14 ] with 394 patients were finally included. The literature screening flow diagram is shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Six studies [ 8 – 11 , 13 , 14 ] reported the intraoperative bleeding of the two methods during the operation. The results of meta-analysis of random effect model showed that there was a significant difference in the intraoperative bleeding between isobar group and PLIF Group [MD = − 124.57; 95% CI (− 200.48, − 48.65); P = 0.001] (Table 2 , Fig.…”

Section: Resultsmentioning

confidence: 99%

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Effects of posterior lumbar nonfusion surgery with isobar devices versus posterior lumbar interbody fusion surgery on clinical and radiological features in patients with lumbar degenerative diseases: a meta-analysis

Guan

Liu

et al. 2022

J Orthop Surg Res

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Purpose The aim of this study was to systematically evaluate the efficacy of posterior lumbar isobar nonfusion with isobar devices versus posterior lumbar interbody fusion (PLIF) in the treatment of patients with lumbar degenerative diseases (LDDs). Materials and method We performed a literature review and meta-analysis in accordance with the Cochrane methodology. The analysis included a Group Reading Assessment and Diagnostic Evaluation assessments, Jadad Quality Score evaluations, and Risk of Bias in Randomized Studies of Interventions assessments. The PubMed, Ovid, EMBASE, Web of Science, MEDLINE, CNKI, VIP and WanFang databases were searched to collect and compare relevant randomized controlled trials and cohort studies of isobar nonfusion and PLIF in the treatment of lumbar degenerative diseases. The retrieval time was from database inception to June 2021. Two evaluators independently screened the literature, extracted data, and evaluated the quality of the included studies. Outcome measures of interest included low back pain, disability, and radiological features. The protocol for this systematic review was registered on INPLASY (2021110059) and is available in full on inplasy.com (https://inplasy.com/inplasy-2021-11-0059/). Results Of the 7 RCTs, 394 patients met the inclusion criteria. The meta-analysis results showed that isobar nonfusion surgery shortened the surgical duration (P = 0.03), reducing intraoperative bleeding (P = 0.001), retained the ROM of surgical segment (P < 0.00001) and the ROM of the lumbar spine (P < 0.00001), and reduced the incidence of ASD (P = 0.0001). However, no significant difference in the postoperative ODI index (P = 0.81), VAS score of LBP (P = 0.59, VAS score of lower limb pain (P = 0.05, and JOA score (P = 0.27) was noted. Conclusions Posterior lumbar nonfusion surgery with isobar devices is superior to PLIF in shortening the surgical duration, reducing intraoperative bleeding, retaining the ROM of surgical segments and the lumbar spine to a certain extent, and preventing ASD. Given the possible publication bias, we recommend further large-scale studies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effects of posterior lumbar nonfusion surgery with isobar devices versus posterior lumbar interbody fusion surgery on clinical and radiological features in patients with lumbar degenerative diseases: a meta-analysis

Guan

Liu

et al. 2022

J Orthop Surg Res

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“…To address these concerns, the researchers are constantly exploring new surgical techniques with the aim of reducing the incidence of iatrogenic injuries to the paraspinal muscles, accelerating the postoperative recovery, and reducing the postoperative low back pain [ 19 , 20 ]. Dynamic stabilization system has been found to decrease adjacent segment degeneration, reduce the loading on the intervertebral disc and improve spinal stability [ 21 , 22 ]. The K-rod internal fixation system is a relatively novel, dynamic spine stability device with a positive clinical outcome recorded in both short and medium terms, which was consisted of titanium alloy pedicle screws, polyetheretherketone (PEEK) rod and titanium alloy tubes [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

The effect of posterior lumbar dynamic fixation and intervertebral fusion on paraspinal muscles

Lin

Xiao

et al. 2021

BMC Musculoskelet Disord

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Background The aim of this study was to analyze the effect of unilateral K-rod dynamic internal fixation on paraspinal muscles for lumbar degenerative diseases. Methods This study retrospectively collected 52 patients who underwent lumbar surgery with the K-rod group or PLIF. The operation time, intraoperative blood loss, postoperative drainage volume, postoperative exercise time were compared in the two groups. The visual analog scale (VAS) score and the oswestry dysfunction index (ODI) were employed to evaluate the clinical outcomes. The functional cross-sectional area (FCSA) of the paraspinal muscles and paraspinal muscles fat infiltration were measured to assess on the paraspinal muscles. Results As compared with the PLIF group, the operation time, the postoperative time in the field, and the average postoperative hospital stay in the K-rod internal fixation group were significantly shortened. At the last follow-up, both the groups showed significant improvement in the VAS score and ODI. The FCSA atrophy of the upper and lower adjacent segments (UAS and LAS) of the K-rod internal group was significantly less than that of the PLIF group. The extent of increase in the fatty infiltration of the paraspinal muscles in the K-rod group was significantly lesser than that in the PLIF group. The postoperative low back pain of the two groups of patients was significantly positively correlated with the FCSA atrophy. Conclusions As compared to PLIF, the posterior lumbar unilateral K-rod dynamic internal fixation showed significantly lesser paraspinal muscle atrophy and fatty infiltration, which were significantly positively correlated with postoperative low back pain.

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“…The incidence of non-diseased intervertebral fixation pseudarthrosis has increased, and with that comes a higher risk of fractures and loosening of internal fixation after surgery; fragmented bones may move apart due to stress shielding making early fusion of the bone graft difficult; and the risk of bone graft absorption and displacement becomes elevated [ 32 , 33 ]. In this study, There were no significant differences between the Cobb angle correction rate and the angle loss between the diseased and the non-diseased intervertebral surgery groups.…”

Section: Discussionmentioning

confidence: 99%

Selection of the fusion and fixation range in the intervertebral surgery to correct thoracolumbar and lumbar tuberculosis: a retrospective clinical study

Yang

Liu

Niu

et al. 2021

BMC Musculoskelet Disord

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Background To compare the diseased verses the non-diseased intervertebral surgery used in the treatment of thoracolumbar and lumbar spinal tuberculosis and to explore the best choice of fusion of fixation range. Methods Two hundred twenty-one patients with thoracolumbar and lumbar tuberculosis were categorized into two groups. One hundred eighteen patients underwent the diseased intervertebral surgery (lesion vertebral pedicle fixation, Group A) and 103 patients underwent the non-diseased intervertebral surgery (1 or 2 vertebral fixation above and below the affected vertebra, group B). Spinal tuberculosis diagnosis was confirmed in both groups of patients before lesion removal, bone graft fusion, and internal fixation. Clinical data and efficacy of the two surgical methods were then evaluated. Results The mean follow-up duration for both procedures was 65 months (50–68 months range). There were no significant differences in laboratory examinations, VAS scores, and the Cobb angle correction rate and the angle loss. However, significant differences existed in the operation time, blood loss, serosanguineous drainage volume, and blood transfusion requirement between the two groups. The diseased intervertebral surgery group performed significantly better than the non-diseased intervertebral surgery group in all of these areas. In both cases, the bone graft fused completely with the normal bone by the last follow-up, occuring at 50–86 months post surgery. Conclusion The diseased intervertebral surgery is a safe and feasible option for the treatment of thoracolumbar and lumbar tuberculosis. It effectively restores the physiological curvature of the spine and reduces the degeneration of adjacent vertebral bodies in the spinal column.

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Analysis of clinical effect and radiographic outcomes of Isobar TTL system for two-segment lumbar degenerative disease: a retrospective study

Cited by 14 publications

References 26 publications

Effects of posterior lumbar nonfusion surgery with isobar devices versus posterior lumbar interbody fusion surgery on clinical and radiological features in patients with lumbar degenerative diseases: a meta-analysis

Effects of posterior lumbar nonfusion surgery with isobar devices versus posterior lumbar interbody fusion surgery on clinical and radiological features in patients with lumbar degenerative diseases: a meta-analysis

The effect of posterior lumbar dynamic fixation and intervertebral fusion on paraspinal muscles

Selection of the fusion and fixation range in the intervertebral surgery to correct thoracolumbar and lumbar tuberculosis: a retrospective clinical study

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