Analysis of Clinical Factors for Survival After Left and Biventricular Bypass Using Centrifugal Pump Following Open Heart Surgery in Infants and Adults

Abstract

A total of eight patients, including three infants, received left or biventricular assist using centrifugal pump (CFP) following open heart surgery. Three infants, aged 9-11 months and with complex cardiac lesions, were supported by left heart bypass (LHB) using pediatric type CFP for 63 h, 64 h, and 13 days. All were weaned from LHB, but long-term survival was not obtained, mainly due to complications. In five adult patients, LHB alone was used in three, and biventricular support in two for 33-240 h with three survivals. The factors related to unsuccessful recovery were delayed start of support and multiorgan failure.

Ventricular assist devices in children: Current achievements and future perspectives

“…Centrifugal pumps and extracorporeal circuits have been used in infants and children since the development of a pediatric centrifugal pump head, Biomedicus (Medtronic, Eden Prairie, MN, USA), in the late 1980s (8–11). Application of these systems is, however, limited to several days or a few weeks at the most, and the patients must remain in the ICU.…”

Percutaneous cardiopulmonary support with heparin-coated circuits in postcardiotomy cardiogenic shock

“…At present, a pigtail catheter inserted into the LV from the contralateral femoral artery is one option for LV decompression, but some limitations remain in terms of whether PCPS promotes LV decompression in the seriously damaged myocardium. 8 Although all patients in our PCPS group were weaned from PCPS without devices other than IABP and recovered from postcardiotomy cardiogenic shock, we propose that PCPS be replaced by ventricular support such as LHB in cases of severe cardiac failure showing no notably improved cardiac function and requiring more effective LV decompression despite use of the pig tail catheter.…”

Development of ventricular assist device and heart transplantation in Japan: How people worked

“…Since early 1980s, Prof. Yukihiko Nosé and his group at the Cleveland Clinic, joined by many Japanese cardiac surgeons, have established a research project centered on chronic nonpulsatile perfusion in large animal models, contributing to development of centrifugal pumps capable of clinical application 26 . For circulatory support to acute hemodynamic collapse, the BP50 centrifugal pump (3M Co., Minneapolis MN, USA) was the main device used as temporary support in various cases of postcardiotomy heart failure 27 . In the early 1990s, extending this acute support using centrifugal pumps, we introduced a portable system of circulatory and respiratory support combining with a membrane oxygenator.…”