Analysis of haemoperfusion columns for evaluation of treatment of phenobarbital overdosage

Fa, de Wolff; Nd, Smit

doi:10.1007/bf00297589

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…A potentially more accurate, but infrequently utilized, alternative method of quantifying the effect of HP is to extrude the poison from the column after it has been used, quantify its content, and compare this to the amount ingested so that the proportion of the dose removed can be calculated .…”

Section: Quantifying the Effect Of Hemoperfusion On Poison Removalmentioning

confidence: 99%

Hemoperfusion for the Treatment of Poisoning: Technology, Determinants of Poison Clearance, and Application in Clinical Practice

Ghannoum

Bouchard

Nolin

et al. 2014

Seminars in Dialysis

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Hemoperfusion is an extracorporeal treatment based on adsorption, historically reserved for the treatment of acute poisonings. Its use was popularized in the 1970s after several in vitro and animal experiments had demonstrated its efficacy, and was even preferred over hemodialysis in the management of overdosed patients. With the advent of new and more efficient dialytic modalities, hemoperfusion is now less frequently performed in the Western world. However, hemoperfusion still remains popular in developing countries. The present article reviews the technique of hemoperfusion, the factors influencing poison clearance through adsorption and its current applications.

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Section: Quantifying the Effect Of Hemoperfusion On Poison Removalmentioning

confidence: 99%

Hemoperfusion for the Treatment of Poisoning: Technology, Determinants of Poison Clearance, and Application in Clinical Practice

Ghannoum

Bouchard

Nolin

et al. 2014

Seminars in Dialysis

View full text Add to dashboard Cite

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Enhanced elimination in acute barbiturate poisoning – A systematic review

Roberts¹,

Buckley

2011

Clinical Toxicology

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There is limited evidence to support the use of enhanced elimination in the treatment of poisoning with most barbiturates. There is no role for urine alkalinisation, while multiple-dose activated charcoal may be useful for most phenobarbital and possibly primidone poisonings. Extracorporeal techniques appear to enhance elimination, but the clinical benefits, relative to the potential complications and cost, are poorly defined. Extracorporeal techniques such as haemodialysis and haemoperfusion can be considered for patients with life-threatening barbiturate toxicity such as refractory hypotension.

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Analysis of haemoperfusion columns for evaluation of treatment of phenobarbital overdosage

Cited by 2 publications

References 4 publications

Hemoperfusion for the Treatment of Poisoning: Technology, Determinants of Poison Clearance, and Application in Clinical Practice

Hemoperfusion for the Treatment of Poisoning: Technology, Determinants of Poison Clearance, and Application in Clinical Practice

Enhanced elimination in acute barbiturate poisoning – A systematic review

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