Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury

Mao, Renqun; Wei, Zean; Li, Wenqing; Zhu, Xiaodi; Du, Dalian; Xu, Wei

doi:10.1155/2021/8294267

Cited by 4 publications

(4 citation statements)

References 18 publications

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“…Анализ топографической анатомии нервных стволов позволил выделить зоны с «суставным» типом сближения концов нерва, когда положение конечности играет существенную роль в этом сближении, и «диафизарные», когда данный аспект существенного значения не имеет [2]. При проведении топографо-анатомического исследования мы установили, что в зонах с «суставным» типом сближения концов поврежденного нерва имеются следующие особенности кровотока нервов: наличие выраженной брыжейки нервных стволов; длина сосудистой ножки кровоснабжающих нерв сосудов позволяет выполнять полный объем поступательных движений нерва; кровообращение нерва в «суставных» зонах из-за на-личия значительной степени подвижности имеет II-III тип [2,3].…”

Section: топографические особенности нервовunclassified

The role of anatomical and topographic features of angioarchitectonics and nerve gliding for its recovery

Kozlov

Fedorova

Anashkina

et al. 2022

Sibirskij nauchnyj medicinskij zhurnal

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In the modern concept of treatment of patients with injuries of peripheral nerves, the main thing is to understand the mechanism of its sliding and the peculiarities of blood supply. Studying the nerve topographic anatomy, we are convinced that the mobility of the nerve exists not only in relation to the tissues surrounding it, but also at the level of its inner bundles. In this article, we report on the different degree of nerve mobility depending on its location zone, and that the ulnar and median nerves have the highest degree of mobility at the level of the forearm distal third. To calculate the change in the glide of the nerves, a mathematical model was constructed to measure their mobility during flexion and extension in the elbow joint, allowing to personalize the flap plasty depending on the length of the autograph vascular pedicle. The anatomical and topographic features of the angioarchitectonics of the nerve at various levels were studied, the presence and variability of the location of the vascular pedicle of blood-supplied autografts were studied. The obtained knowledge is necessary for carrying out revascularization of the damaged nerve zone with various types of autografts with autonomous blood flow. Conclusions. Knowledge of the anatomical and topographic features of peripheral nerves, their blood supply and mobility is necessary for their recovery for various injuries.

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Section: топографические особенности нервовunclassified

The role of anatomical and topographic features of angioarchitectonics and nerve gliding for its recovery

Kozlov

Fedorova

Anashkina

et al. 2022

Sibirskij nauchnyj medicinskij zhurnal

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“…However, further improvement of the repair effect is required, especially for large segmental peripheral nerve defects. The interrupted connection between the injured proximal and distal nerve fibers makes the repair more difficult in clinical treatment ( 6 , 7 ).…”

Section: Introductionmentioning

confidence: 99%

Experimental study on the repair of peripheral nerve injuries via simultaneously coapting the proximal and distal ends of peripheral nerves to the side of nearby intact nerves

Li¹,

Yang

Liu³

et al. 2023

Front. Neurol.

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IntroductionPeripheral nerve defect is a difficult disease to treat in clinical practice. End-to-side anastomosis is a useful method to treat it. At present, the end-to-side anastomosis method does not involve the proximal nerve, which results in a waste of proximal donor nerves, and even the formation of traumatic neuromas at the proximal end. The patients suffer from traumatic neuralgia and the curative effect is unsatisfactory.MethodsIn this study, an improved end-to-side anastomosis technique was proposed in this study: both the proximal and distal ends of the damaged common peroneal nerve were sutured to an adjacent normal tibial nerve. Moreover, the possible role and mechanism of the proposed technique were explained at the physiological and anatomical levels. In this study, a 10 mm common peroneal nerve defect was made in SD rats, and the rats were randomly divided into three groups. In Group I, the distal end of the common peroneal nerve was attached end-to-side to the fenestrated tibial nerve adventitia, and the proximal end was ligated and fixed in the nearby muscle. In Group II, the tibial nerve adventitia was fenestrated and the epineurial end-to-end anastomosis surgery was performed to suture the proximal and distal ends of the common peroneal nerve. Rats in Group III were taken as control and received sham operation. Twelve weeks after the operation, the recovery of the repaired nerve and distal effector functions were examined by the sciatic functional index, electrophysiology, osmic acid staining, the muscle wet weight ratio, and the muscle fiber cross-sectional area.ResultsIt was found that these results in Group II were similar to those in Group III, but better than those in Group I. Through retrograde tracing of neurons and Electrophysiological examination in Group II, the study also found that the proximal common peroneal nerve also could establish a connection with tibialis anterior, even gastrocnemius.DiscussionTherefore, it is inferred that fostering both the proximal and distal ends of defective peripheral nerves on normal peripheral nerves using the end-to-side anastomosis technique is a more effective approach to repairing injured nerves.

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“…Computational and Mathematical Methods in Medicine has retracted the article titled “Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury” [ 1 ] due to concerns that the peer review process has been compromised.…”

mentioning

confidence: 99%

“…Computational and Mathematical Methods in Medicine has retracted the article titled "Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury" [1] due to concerns that the peer review process has been compromised. Following an investigation conducted by the Hindawi Research Integrity team [2], significant concerns were identified with the peer reviewers assigned to this article; the investigation has concluded that the peer review process was compromised.…”

mentioning

confidence: 99%

Retracted: Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury

Medicine¹

2022

Computational and Mathematical Methods in Medicine

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Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury

Cited by 4 publications

References 18 publications

The role of anatomical and topographic features of angioarchitectonics and nerve gliding for its recovery

The role of anatomical and topographic features of angioarchitectonics and nerve gliding for its recovery

Experimental study on the repair of peripheral nerve injuries via simultaneously coapting the proximal and distal ends of peripheral nerves to the side of nearby intact nerves

Retracted: Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury

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