Analysis of iridoid glucosides from Paederia scandens using HPLC–ESI-MS/MS

Simultaneous ligand fishing and identification of human serum albumin binders from Eucommia ulmoides bark using surface plasmon resonance-high performance liquid chromatography–tandem mass spectrometry

“…In addition, the fragment ion at m/z 123.0407 was yielded by the RDA rearrangement from the fragment ion at m/z 193.0503. All the cleavage rules and fragmentation pathways coincided well with the published data [28]. Compound 9 had similar UV spectrum with that of 3, which showed a [M−H] − ion at m/z 387.1285 (C 17 H 23 O 10 , −1.6 ppm error, 14 Da greater than that of 3), indicating the presence of a methyl group.…”

Recent (2000–2015) developments in the analysis of minor unknown natural products based on characteristic fragment information using LC–MS

“…Unfortunately, many interesting low‐abundance precursor ions cannot be captured by auto‐MS/MS experiments. Wu et al applied manual adjustment of mass spectrometry parameters on the fly to obtain high‐quality MS/MS spectra of low‐abundance precursor ions (Wu et al, , ). Muller et al established a data mining workflow based on MS/MS precursor lists targeting only signals related to bacterial metabolism using LC–MS data of crude extracts from shaking flask fermentations (Hoffmann et al, ).…”

Analyses of the Iridoid Glucoside Dimers in Paederia scandens Using HPLC–ESI–MS/MS

“…Compounds 9–13 are isomers and the accurate masses of the [M + NH 4 ] + ions for compounds 9–13 correspond to the molecular formula C 36 H 46 O 23 S, only one S atom is different from compounds 1–4 . Compound 11 was reported in our previous work and condensed from paederoside and asperulosidic acid (Wu et al ., ). However, the linkage site cannot be confirmed.…”