Analysis of Kidney Biopsy Data From a Single Center in the Midland Rural Area of China, 1996–2010

Wang, Yongtao; Zhou, Chenyan; Zhu, Tie-Chui; Yang, Jun; Zhang, Yan; Xu, Qingyu; Guο, Minghao

doi:10.1016/j.curtheres.2012.12.005

Cited by 7 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the male to female ratio was 1.7:1 which is similar to various Indian and international studies [7][8][9][10]. Although there was an overall male preponderance, both in the groups under 40 years of age, females were more in number than males.…”

Section: Discussionsupporting

confidence: 90%

Pattern of kidney diseases in Northern India: an overview through histopathological findings in biopsy-proven cases

Kumar

Kumari

Agrawal³

2020

Egypt J Intern Med

View full text Add to dashboard Cite

Background A kidney biopsy is being increasingly performed for the diagnosis of renal diseases. It is a reasonably safe procedure that helps not only to reach the correct diagnosis based on histopathological findings but also helps in predicting the clinical course and outcome. The pattern of kidney diseases varies not only in far apart geographical regions but also in the same country. This study was done to evaluate the demographic pattern and spectrum of kidney diseases in renal biopsy-proven cases in an admitted patient of a tertiary care hospital of northern India. Results The mean age of patients was 41.3 years ± 18.39 years, and the male-to-female ratio was 1.7:1. The most common indication for biopsy in this study was nephrotic syndrome (40.5%). The primary glomerular disease was most common, accounting for 57.5% of cases. Membranous nephropathy (MN) was the most frequently observed histopathological diagnosis not only in the primary glomerular disease category (22.9%) but of all cases (13.2%) as well. Among secondary cases, diabetic nephropathy was most frequent, constituting 43.4% cases. Interstitial and vascular diseases accounted for 18.8% and 1.8% of total cases, respectively. While minimal change disease (MCD) was the most common diagnosis in < 18-year age group, membranous nephropathy was most common above this age. Regarding the gender factor, membranoproliferative glomerulonephritis had an equal distribution among both genders, while MCD had a female preponderance. Conclusions Primary glomerular disease is the predominant kidney disease in northern India with MN being the most common histopathological diagnosis. The spectrum of kidney diseases varied with patient’s age and gender.

show abstract

Section: Discussionsupporting

confidence: 90%

Pattern of kidney diseases in Northern India: an overview through histopathological findings in biopsy-proven cases

Kumar

Kumari

Agrawal³

2020

Egypt J Intern Med

View full text Add to dashboard Cite

show abstract

“…There was no doubt that primary GD was the most common renal diseases, accounting for 81.55% in our study, and it was within the range of 61.7-82.7% reported from other centers in China. 4,5,8,25,26 No significant change in the prevalence of primary GD was found in our study, while the prevalence of secondary GD increased (9.13% in period 1 versus 14.15% in period 4) (p < 0.05), probably because of the improvement in the recognition of these diseases and diagnostic technology, and its substantial change as well. The frequency of IgAN was markedly different because of regional differences, with the highest in Asian countries (36.7-54.3%), [4][5][6][7][8] Nevertheless, we found that there was a gradual increase in MCD, from 0.34% in period 2 to 2.68% in period 4 (p < 0.001), and this phenomenon could be observed in other study of China.…”

Section: Discussionmentioning

confidence: 42%

“…It has been reported that NS was the main indication for renal biopsy in other countries 10,12,14,22 and northern China. 4,24,26 However, in our study, we found that proteinuria and hematuria rather than NS was the most frequent cause for renal biopsy, making up almost half of the patients (49.03%), and NS ranked the second (20.36%). There was no doubt that primary GD was the most common renal diseases, accounting for 81.55% in our study, and it was within the range of 61.7-82.7% reported from other centers in China.…”

Section: Discussionmentioning

confidence: 46%

“…Due to the improvement in economic conditions, enhancement of health consciousness and advancement in technology level and safety of renal biopsy, the number of patients receiving renal biopsy was increased dramatically during the four periods, as well as the average age when renal biopsy performed and the number of patients over 60 years old (p < 0.05), consistent with the reports from Beijing and Shanghai. 4,25 Interestingly, the patients with renal biopsy in our study was female dominated (54.3%), that was different from others in China 4,8,25,26 except Harbin, 24 and regional differences may be the main reason. It has been reported that NS was the main indication for renal biopsy in other countries 10,12,14,22 and northern China.…”

Section: Discussionmentioning

confidence: 67%

“…12,13 Recently, an increasing number of studies demonstrate that the spectrum of biopsy-proven renal diseases has changed over the past three decades in other counties 7,11,[13][14][15][16][17][18][19][20][21][22][23] and in northern and southern China. 4,8,24,25 Nephrotic syndrome (NS) is reported to be the main indication for renal biopsy in other countries 10,12,14,22 and northern China, 4,24,26 except Japan, 6 where the leading indication is asymptomatic proteinuria and/or hematuria. However, limited information is available on changing spectrum and clinicopathologic correlation of biopsy-proven renal diseases in central China.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Analysis of 4931 renal biopsy data in central China from 1994 to 2014

Ning

Shi

et al. 2016

Renal Failure

View full text Add to dashboard Cite

The purpose of this study is to investigate the changing spectrum and clinicopathologic correlation of biopsy-proven renal diseases in central China. We retrospectively analyzed data of 4931 patients who underwent renal biopsy in ten hospitals between September 1994 and December 2014. Among them, 81.55% were primary glomerular diseases (GD), and 13.02% were secondary GD. IgA nephropathy (IgAN) was the most common primary GD (43.45%), followed by focal glomerulonephritis (16.79%), mesangial proliferative glomerulonephritis (MsPGN, 14.35%), and membranous nephropathy (MN, 13.28%). IgAN was leading primary GD in patients under 60 years old, while MN was the leading one over 60 years old. The most frequent secondary GD was lupus nephritis (LN) (47.35%). The prevalence of IgAN, MN and minimal change disease was found to increase significantly (p < 0.001, p < 0.001, and p < 0.01, respectively), while that of MsPGN, membranoproliferative glomerulonephritis and LN decreased significantly (p < 0.001, p < 0.001, and p < 0.05, respectively). The main indication for renal biopsy was proteinuria and hematuria (49.03%), followed by nephrotic syndrome (NS, 20.36%). IgAN was the most common cause in patients with proteinuria and hematuria, chronic-progressive kidney injury, hematuria and acute kidney injury; and MN was the leading cause of NS. Primary GD remained the predominant renal disease in central China. IgAN and LN were the most prevalent histopathologic lesions of primary and secondary GD, respectively. The spectrum of biopsy-proven renal disease had a great change in the past two decades. Proteinuria and hematuria was the main indication for renal biopsy. ARTICLE HISTORY

show abstract

Clinicopathological spectrum of biopsy-proven renal diseases of patients at a single center in Sri Lanka: a cross sectional retrospective review

et al. 2023

View full text Add to dashboard Cite

Background The clinical presentation of renal diseases can vary widely. The lack of a comprehensive national registry for Sri Lanka makes it difficult to provide a detailed record of the various clinical presentations and histopathology of renal disorders in the nation. Therefore, this study aims to provide a record of the spectrum of renal diseases in Sri Lanka. Methods Renal biopsies performed at the nephrology unit in Colombo South Teaching Hospital (CSTH), Sri Lanka from March 2018 to October 2019 was retrospectively studied. Indications for renal biopsy were nephrotic range proteinuria, sub nephrotic range proteinuria, acute kidney injury without obvious etiology, chronic renal disease without obvious etiology and haematuria. Results A total of 140 native kidney biopsies were analyzed in which majority were females (55.7%). The mean age of the population was 46 ± 15.3 years. The most common indications for renal biopsy were nephrotic range proteinuria (54.3%), followed by sub-nephrotic range proteinuria (14.3%), nephrotic range proteinuria with haematuria (14.3%), sub-nephrotic range proteinuria with haematuria (9.3%), AKI without known cause (4.3%), and CKD without known cause (3.6%). The leading histopathological diagnoses were FSGS (22.1%), lupus nephritis (20%), PSGN (17.1%), DN (12.1%), HTN (9.3%), MCD (6.4%), IgA nephropathy (5.7%), IN (4.3%), vasculitis (2.1%), and MGN (0.7%). Conclusions The most common indication for renal biopsy was nephrotic range proteinuria in our population. FSGS was the most prevalent histopathological diagnosis and the least frequent diagnosis reported was MGN. The spectrum of renal diseases could differ according to the study location and it changes over time. Therefore, a renal biopsy registry is needed for documenting the changing disease pattern in Sri Lanka.

show abstract

Analysis of Kidney Biopsy Data From a Single Center in the Midland Rural Area of China, 1996–2010

Cited by 7 publications

References 7 publications

Pattern of kidney diseases in Northern India: an overview through histopathological findings in biopsy-proven cases

Pattern of kidney diseases in Northern India: an overview through histopathological findings in biopsy-proven cases

Analysis of 4931 renal biopsy data in central China from 1994 to 2014

Clinicopathological spectrum of biopsy-proven renal diseases of patients at a single center in Sri Lanka: a cross sectional retrospective review

Contact Info

Product

Resources

About