Analysis of microsatellite DNA polymorphism in the Tatra Shepherd Dog

Radko, Anna; Rubiś, Dominika; Szumiec, Anna

doi:10.1080/09712119.2017.1292912

Cited by 14 publications

(23 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is genetically well distinguished from other livestock guard dogs from the Western Balkans, Karst Shepherd and Tornjak [25]. We report levels of genetic diversity in YSD which are in the range of those reported by Dimitrijević [2008] and Ceh and Dovc [25], and are comparable and in some cases even higher than those found in numerous dog breeds studied to date by means of nuclear microsatellites [4,[11][12][13][14][15][16][17][18][19][20][21][22][23]. Thus, despite the decline of the YSD population after both 20 th century World Wars, this breed remains genetically highly diverse.…”

Section: Discussionsupporting

confidence: 70%

“…That, along with the historical variations in population sizes, have resulted in the considerable inbreeding and loss of genetic variability in certain purebred dog populations [5][6][7][8], as well as in the increased incidence of inherited diseases [9][10][11]. Although genetic make-up of numerous dog breeds has been studied to date [4,[11][12][13][14][15][16][17][18][19][20][21][22][23], the knowledge regarding genetic structure of non-cosmopolitan dog breeds and local canine populations is still grossly lacking [21,24].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

et al. 2020

View full text Add to dashboard Cite

Yugoslavian Shepherd Dog - Sharplanina (YSD) is a livestock guard dog from the Western Balkans present in this region over a long time, but recognized by the Fédération Cynologique Internationale as a distinct breed as late as 1957. However, the information regarding the origin and the size of the breed’s foundation stock is still lacking. In order to contribute towards better understanding of the genetic make-up of the YSD and its foundation stock, we re-analyzed previously generated genetic profiles of 94 registered YSD dogs assessed with nine nuclear microsatellites. Studied individuals comprised 90 unrelated dogs and two pairs of full-sibs, sampled at four sampling sites: three dog shows and at a military training centre for dogs in Serbia. We supported earlier findings on high levels of genetic diversity in YSD (HE=0.728±0.027) and lack of inbreeding, and revealed substructure of the breed because we found two distinct gene pools in the Bayesian clustering analysis, indicated also by the excess of homozygotes (i.e., Wahlund effect) and outcomes of other analyses: linkage disequilibrium tests, Neighbour-Joining tree, principal coordinates and two-dimensional scaling analyses. The two gene pools were almost equally represented at each sampling site. One gene pool was composed of individuals with high genetic integrity, while the other gene pool was characterized with admixed ancestry, developed possibly via hybridization with native breeding stock outside the registry system, other breeds, such as the Caucasian Shepherd, and/or individuals admixed with wolves. Thus, we demonstrate rather complex and diverse ancestry implying a genetically heterogeneous foundation stock of the YSD.

show abstract

Section: Discussionsupporting

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The variations in the population of Tatra Shepherd Dogs have been shown by Radko et al [37]. The DNA polymorphism analysis demonstrated a considerable genetic differentiation of microsatellite markers and the lack of inbreeding in the analysed population of Tatra Shepherd dogs.…”

Section: Introductionmentioning

confidence: 61%

“…A way of enriching the line can be reaching the descendants of such dogs that are not shown at dog shows and obtaining genetic material by entering them into the stud book and then using them for breeding. Therefore, the import of Tatra Shepherd dogs bred in the Netherlands or France that show a low degree of kinship with dogs in Poland can be an excellent choice to abandon extensive inbreeding, and aim at improving the breed [22, 36, 37, 49].…”

Section: Discussionmentioning

confidence: 99%

Analysis of structure of the population, kinship coefficients and inbreeding trend depending on sex, type of breeding of Tatra Sheepherd dogs

Edyta

Elżbieta

Roman

2020

Preprint

View full text Add to dashboard Cite

14The aim of the study was to analyse the structure of the population, kinship coefficients and 15 inbreeding trend taking into account the sex, breeding system: champions (CH) and non-16 champions (nCH), breeding country: Poland (PL) and foreign country (Z) and the inbreeding 17 degree of Tatra Shepherd dogs. Out of the currently registered 587 Tatra Shepherd dogs, 18 41.9% have been qualified for breeding. In the past decade, 1961 puppies were born, which 19 corresponds to an average litter of 5.8 puppies. The breed's inbreeding rate amounted to 20 6.34%, and for a 4-generation population was 6.68%. The highest inbreeding rate was found 21 in nCH and PL groups consisting of both male and female dogs. The inbreeding rate was 22 significantly higher in 2005-2014 compared to the years 1994-2004. The limit value F X was 23 exceeded for 25.65% of Shepherd dogs, and the critical value was exceeded for 11.52%. An 24 increasing ancestor loss coefficient (AVK) was found, which may result in an increased 25 number of inbred animals. In particular, it referred to female dogs in the nCH, PL, and F 26 group, whereas a significant increase of AVK was observed in the group of male dogs from 2 27 foreign kennels. The resulting COR values, respectively 55.58% for males and 55.44% for 28 females, testify to insignificant inbreeding and suggest that breeders look for male inbreds. 29 Studies have shown that there is no risk of inbred depression yet; however, the gene pool of 30

show abstract

“…Microsatellites, mtDNA and biochemical markers were often used for this purpose [ 18 ]. Microsatellites and population characteristics based on these neutral markers characterize the general level of genetic diversity, population structure and evolutionary relationships between populations and subpopulations [ 19 – 22 ]. Microsatellites were used for characterizing neutral genetic variation between and within dog populations [ 8 , 23 ] as well as for African village dogs [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Genetic diversity and population structure of African village dogs based on microsatellite and immunity-related molecular markers

et al. 2018

View full text Add to dashboard Cite

The village and street dogs represent a unique model of canine populations. In the absence of selective breeding and veterinary care, they are subject mostly to natural selection. Their analyses contribute to understanding general mechanisms governing the genetic diversity, evolution and adaptation. In this study, we analyzed the genetic diversity and population structure of African village dogs living in villages in three different geographical areas in Northern Kenya. Data obtained for neutral microsatellite molecular markers were compared with those computed for potentially non-neutral markers of candidate immunity-related genes. The neutral genetic diversity was similar to other comparable village dog populations studied so far. The overall genetic diversity in microsatellites was higher than the diversity of European pure breeds, but it was similar to the range of diversity observed in a group composed of many European breeds, indicating that the African population has maintained a large proportion of the genetic diversity of the canine species as a whole. Microsatellite marker diversity indicated that the entire population is subdivided into three genetically distinct, although closely related subpopulations. This genetical partitioning corresponded to their geographical separation and the observed gene flow well correlated with the communication patterns among the three localities. In contrast to neutral microsatellites, the genetic diversity in immunity-related candidate SNP markers was similar across all three subpopulations and to the European group. It seems that the genetic structure of this particular population of Kenyan village dogs is mostly determined by geographical and anthropogenic factors influencing the gene flow between various subpopulations rather than by biological factors, such as genetic contribution of original migrating populations and/or the pathogen-mediated selection. On the other hand, the study of oldest surviving dogs suggested a biological mechanism, i.e. a possible advantage of the overal heterozygosity marked by the the microsatellite loci analyzed.

show abstract

Analysis of microsatellite DNA polymorphism in the Tatra Shepherd Dog

Cited by 14 publications

References 7 publications

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

Analysis of structure of the population, kinship coefficients and inbreeding trend depending on sex, type of breeding of Tatra Sheepherd dogs

Genetic diversity and population structure of African village dogs based on microsatellite and immunity-related molecular markers

Contact Info

Product

Resources

About