Analysis of Phenobarbital in Relation to its Degradation Products

Stable Nonaqueous Pentobarbital Sodium Solutions for Use in Laboratory Animals

“…All data were treated statistically, using linear regression analyses to establish rate constants and confidence intervals (7). Assay-A differential UV method, similar to that reported by Tishler et al (8) for phenobarbital degradation, was used to assay the remaining pentobarbital sodium. The sample was diluted in 1.0 N NH40H to a concentration of 4-20 pglml of pentobarbital sodium, and a UV spectrum from 220 to 300 nm was obtained2.…”