Analysis of phenolic compounds and antioxidant activity of methanolic extracts from inflorescences of Carduus sp

Kozyra, Małgorzata; Komsta, Łukasz; Wojtanowski, Krzysztof Kamil

doi:10.1016/j.phytol.2019.04.012

Cited by 17 publications

(14 citation statements)

References 19 publications

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“…On the other hand, Krishna et al (2014) shows that 200 μg of p-coumaric acid generate an inhibition halo in the development of S. aureus by means of disk diffusion tests. In S. epidermidis, a MIC of 1000 μg / mL was determined, similar to that previously reported for the strain type S. epidermidis ATCC 12228 (Kozyra et al 2019), and lower than that reported by Alves et al (2013) who suggest that the MIC for S. epidermidis is greater than 1000 μg / mL. Regarding Gram negative bacteria, for P. aeruginosa ATCC 30298 a MIC of 500 μg / mL was determined.…”

Section: Journal Of Natural and Agricultural Sciencessupporting

confidence: 84%

“…Regarding vanillic acid, it was determined that the concentrations used did not inhibit the development of the Gram-positive microorganisms evaluated, suggesting that the MIC is higher than 1000 μg / mL. The doses determined in this study are similar to those reported by Kozyra et al (2019) for S. epidermidis ATCC 12228, who show that the MIC is greater than 1000 μg / mL. On the other hand, it has been shown that vanillic acid does not inhibit the development of the type strains, S. aureus ATCC 6538 and S. aureus ATCC 25923 (Kozyra et al 2019).…”

Section: Journal Of Natural and Agricultural Sciencessupporting

confidence: 80%

“…The effect of pcoumaric acid against S. aureus is controversial, because studies in this regard report different MIC doses from each other, which may be due to the technique used and the strains evaluated in the determinations. Alves et al (2013) suggests that p-coumaric acid exerts antimicrobial activity against sensitive (MSSA) and methicillin resistant (MRSA) S. aureus at a MIC greater than 1000 μg / mL, while Kozyra et al (2019) found no activity of p-coumaric acid against the type strains of S. aureus ATCC 6538 and S. aureus ATCC 25923.…”

Section: Journal Of Natural and Agricultural Sciencesmentioning

confidence: 99%

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Antibacterial activity of Costus pulverulentus (Costaceae) C. Presl

Ramiro-Bautista

Morales

Carranza‐Álvarez

et al. 2020

JNAS

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Antimicrobial resistance is a great concern in public health. Therefore, it is necessary to obtain new compounds to treat diseases caused by bacteria. Medicinal plants are an alternative to search natural compounds to improve human health, including antioxidants, anti-inflammatory, and antimicrobials compounds. Costus pulverulentus (Costaceae) C. Presl is a plant used traditionally in Huasteca Potosina to treat bacterial infections. However, the compounds involved in this activity remain poorly understood. To determine the antibacterial activity of C. pulverulentus, an ethanolic extract was obtained. Plant stem was macerated in ethanol and then was fractionated with hexane, chloroform, ethyl acetate, acetone, ethanol, and methanol. Ethanolic extract and derived fractions were tested against bacteria by the disk-diffusion agar method. The results showed that the ethanolic extract of C. pulverulentus exerted activity against Chromobacterium violaceum CV026 and Bacillus sp. at 10 and 30 μg/disk, whereas only the methanolic fraction showed similar activity to complete extract. Fraction 8 obtained from methanolic fraction showed inhibitory activity against Bacillus sp., S. aureus, and S. aureus Oxacillin resistant. Gas Chromatography-Mass Spectrometry characterization of active fraction 8 showed that it contains vanillic acid and pcoumaric acid suggesting that they are involved in the antibacterial activity of C. pulverulentus.

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Section: Journal Of Natural and Agricultural Sciencessupporting

confidence: 84%

Section: Journal Of Natural and Agricultural Sciencessupporting

confidence: 80%

Section: Journal Of Natural and Agricultural Sciencesmentioning

confidence: 99%

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Antibacterial activity of Costus pulverulentus (Costaceae) C. Presl

Ramiro-Bautista

Morales

Carranza‐Álvarez

et al. 2020

JNAS

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“…Only chlorogenic and 3,5-DCQ acids were also correlated with TotP, NTP, TP and TotF. According to Kozyra et al [41], chlorogenic acid significantly influence the antioxidant activity of methanolic extracts from inflorescences of Carduus sp. In Loquat (Eriobotrya japonica Thunb.…”

Section: Rp-hplc Analysis Of Phenolic Compoundsmentioning

confidence: 95%

Bioactive Compounds from Leaves and Twigs of Guayule Grown in a Mediterranean Environment

Piluzza

Campesi

Molinu

et al. 2020

Plants

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Guayule (Parthenium argentatum) is one of the most promising alternatives to produce natural rubber. As the guayule leaves represent a waste byproduct in the rubber extraction process, their exploitation might contribute to the valorization of the whole plant biomass. The specific aim of our study was to determine the antioxidant capacity and the content of phenolic compounds in leaves and twigs of different guayule lines cultivated in a Mediterranean environment. The antioxidant capacity and the contents of phenolic were affected significantly by guayule accession and harvest time. Overall means in twigs represented about 60% of the corresponding leaf values for antioxidant capacity as DPPH (1,1-diphenyl-2-picrylhydrazyl) and not tannic phenolic and about 55% as ABTS (2,2′-azinobis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt), total phenolic, tannic phenolic and total flavonoid contents. Five individual phenolic compounds were identified in methanolic extracts of leaves. Neochlorogenic acid (62.5–174.8 mg g−1 DW) and chlorogenic acid (28.6–41.1 mg g−1 DW) were the most abundant phenolic acids. In addition to the compounds quantified in leaves, cynarin was identified only in twigs and for the first time in guayule biomass. Our results indicate that guayule leaves and twigs represent a rich source of antioxidants for potential applications in fodder, nutraceutical and pharmacological sectors.

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“…Moreover, the documentation of indigenous knowledge is important for conservation of the medicinal values of plants and drug discovery (de Brum et al 2016). Recently, use of traditional medicines attracted considerable amount of interest of several researchers due to its potentialities antioxidant properties (Kozyra et al 2019;Xiang et al 2019) and attributed to the ion donating or decomposing reactive oxygen species (ROS) ability of phenolic compounds.…”

Section: Introductionmentioning

confidence: 99%

Tupistra nutans Wall. root extract, rich in phenolics, inhibits microbial growth and α-glucosidase activity, while demonstrating strong antioxidant potential

Chung

Chelliah

et al. 2019

Braz. J. Bot

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The current study was performed to determine the phenolic compounds composition, antioxidant and antimicrobial activity, and α-glucosidase inhibitory effect of the root extract of Tupistra nutans Wall., in order to validate its use in traditional medicine. HPLC-MS/MS analysis showed the presence of ferulic acid, protocatechuic acid, p-hydroxybenzoic acid, p-coumaric acid, salicylic acid, chlorogenic acid, caffeic acid, l-phenylalanine as the predominant phenolic compounds. The antioxidant potentials of T. nutans were determined in different solvent extract and found to vary in a concentration-dependent manner. Ethyl acetate-soluble fraction exhibited the highest amount of phenolic acids, flavonoids, antioxidant activity against the DPPH, reduced Fe 3+ /ferric cyanide complexes to the ferrous form and inhibitory effect on α-glucosidase. Butanol fraction showed the strongest ABTS radical scavenging ability. Methanolic root extract showed higher reduction capability of ferric ions than the other solvent fractions. A significant and higher positive correlation was found between total phenolic content and total flavonoid content with α-glucosidase inhibition and DPPH using ethyl acetate solvent than the other solvent fractions. All the tested microorganisms: Staphylococcus aureus Rosenback (ATCC13150), Salmonella enterica typhimurium Kauffmann and Edwads (ATCC14028), Escherichia coli Castllani and Chalmers (ATCC35150), and fungi: Candida albicans Robin and Berkhout (KTCC7965), Aspergillus fumigatus Fresenius (KTCC6145), A. flavus var. flavus Link ex Fries (KTCC6143), A. niger van Tieghem (KTCC6317) were susceptible to the root extracts at a concentration of 0.12-0.25 mg mL −1. This study may allow us to understand indigenous medicinal values of T. nutans. Furthermore, these results showed that T. nutans is a good source of antioxidants along with antimicrobial and antidiabetic activities and could be used as an important bioresource for the pharmaceutical and food industries.

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Analysis of phenolic compounds and antioxidant activity of methanolic extracts from inflorescences of Carduus sp

Cited by 17 publications

References 19 publications

Antibacterial activity of Costus pulverulentus (Costaceae) C. Presl

Antibacterial activity of Costus pulverulentus (Costaceae) C. Presl

Bioactive Compounds from Leaves and Twigs of Guayule Grown in a Mediterranean Environment

Tupistra nutans Wall. root extract, rich in phenolics, inhibits microbial growth and α-glucosidase activity, while demonstrating strong antioxidant potential

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