Analysis of shape features for lesion classification in breast ultrasound images

Khusna, Dina Arifatul; Nugroho, Hanung Adi; Soesanti, Indah

doi:10.1063/1.4958602

Cited by 6 publications

(2 citation statements)

References 8 publications

(6 reference statements)

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“…The parameter "compactness" is measured by dividing spheroid area by its squared perimeter, with the circle being the object with the most compact shape and, therefore, with the maximum value of compactness, which is 1 [48]. Finally, solidity, which is an indicator of the roughness of the spheroidal surface, was determined in order to assess spheroids' regularity [49].…”

Section: Morphological Analysismentioning

confidence: 99%

Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin

Zingales,

Esposito,

Quagliata

et al. 2024

Foods

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Mycotoxins are secondary metabolites produced by filamentous fungi associated with a variety of acute and chronic foodborne diseases. Current toxicology studies mainly rely on monolayer cell cultures and animal models, which are undeniably affected by several limitations. To bridge the gap between the current in vitro toxicology approach and the in vivo predictability of the data, we here investigated the cytotoxic effects induced by the mycotoxins sterigmatocystin (STE), ochratoxin A (OTA) and patulin (PAT) on different 2D and 3D cell cultures. We focused on human tumours (neuroblastoma SH-SY5Y cells and epithelial breast cancer MDA-MB-213 cells) and healthy cells (bone marrow-derived mesenchymal stem cells, BM-MSC, and umbilical vein endothelial cells, HUVECs). The cytotoxicity of STE, OTA, and PAT was determined after 24, 48 and 72 h of exposure using an ATP assay in both culture models. Three-dimensional spheroids’ morphology was also analysed using the MATLAB-based open source software AnaSP 1.4 version. Our results highlight how each cell line and different culture models showed specific sensitivities, reinforcing the importance of using more complex models for toxicology studies and a multiple cell line approach for an improved and more comprehensive risk assessment.

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Section: Morphological Analysismentioning

confidence: 99%

Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin

Zingales,

Esposito,

Quagliata

et al. 2024

Foods

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“…Major axis length mengalami kendala ketika dilakukan normalisasi rotasi karena sensitif terhadap noise [7]. Persamaan aspek rasio [8][9] adalah rasio antara major axis length dengan minor axis length, sehingga aspek rasio juga tidak dapat dijadikan sebagai fitur yang invariant tehadap rotasi [10]. Perhitungan GLCM sensitif terhadap noise [11].…”

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Klasifikasi Sel Serviks Pada Citra Pap Smear berdasarkan Fitur Bentuk Deskriptor Regional dan Fitur Tekstur Uniform Rotated Local Binary Pattern

Sholik

Fatichah

2017

JUTI

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ABSTRAK Perubahan orientasi objek pada saat akuisisi memerlukan metode ekstraksi fitur yang invariant terhadap rotasi. Ekstraksi fitur tekstur yang telah digunakan dalam kombinasi fitur sebelumnya untuk klasifikasi sel serviks pada dataset Herlev antara lain homogenitas GLCM dan Local Binary Pattern Histogram Fourier (LBP-HF I. PENDAHULUANANKER serviks merupakan penyebab utama keempat kematian kanker pada wanita di dunia [1]. Hal ini dapat dicegah jika diperiksa pada tahap prakanker [2]. Kanker serviks terjadi karena adanya perkembangan sel-sel abnormal secara cepat dan tidak terkendali pada leher rahim [3]. Papanicolaou test adalah langkah pertama dalam pemeriksaan kanker serviks [3]. Hasil pemeriksaan akan menunjukkan kondisi sel serviks normal atau abnormal. Pemeriksaan terdiri dari pengumpulan sampel sel dari daerah tertentu pada serviks, kemudian sampel sel diamati melalui mikroskop dan didiagnosis oleh ahli sel secara manual [4]. Analisis hasil pemeriksaan secara manual memerlukan waktu yang lama dan rawan terhadap kesalahan sehingga dibutuhkan proses klasifikasi sel serviks pada citra pap smear berbasis komputer.Adanya perubahan orientasi sel pada saat akuisisi akan mempengaruhi nilai fitur yang dihasilkan [5] sehingga menjadi dasar pada penelitian ini. Tidak semua fitur dapat menghasilkan fitur yang sama jika citra sel yang sama mengalami perubahan orientasi sehingga dibutuhkan metode ekstraksi fitur yang invariant terhadap rotasi.

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Classification Model for Easily Confused Breast Ultrasound Image Based on Shape and Texture Features

Wang¹

2023

Lecture Notes in Electrical Engineering

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Analysis of shape features for lesion classification in breast ultrasound images

Cited by 6 publications

References 8 publications

Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin

Comparative Study of Spheroids (3D) and Monolayer Cultures (2D) for the In Vitro Assessment of Cytotoxicity Induced by the Mycotoxins Sterigmatocystin, Ochratoxin A and Patulin

Klasifikasi Sel Serviks Pada Citra Pap Smear berdasarkan Fitur Bentuk Deskriptor Regional dan Fitur Tekstur Uniform Rotated Local Binary Pattern

Classification Model for Easily Confused Breast Ultrasound Image Based on Shape and Texture Features

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