2003
DOI: 10.1002/bimj.200390005
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Analysis of the Binary Littermate Data in the One‐Way Layout

Abstract: SummaryIn certain experiments with laboratory animals like rodents, it is common to observe the binary littermate data that the fetuses in the same litter provide a set of independent Bernoulli responses conditional on the litter specific abnormal probability. For testing homogeneity of abnormal proportions of several groups, five methods are discussed in the frame of the one-way layout with litter effects. Simulation results show a superiority of the Rao-Scott procedure.

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Cited by 2 publications
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“…The analysis of highly correlated multiple binary endpoints were discussed in the context of neurotoxocity assays (Han et al, 2004). Lee (2003) described the analysis of binary littermate data like death or the malformation rate for several k-sample tests including the assumption of beta-binomial distribution. The direct inclusion of the assay sensitivity, i.e.…”
mentioning
confidence: 99%
“…The analysis of highly correlated multiple binary endpoints were discussed in the context of neurotoxocity assays (Han et al, 2004). Lee (2003) described the analysis of binary littermate data like death or the malformation rate for several k-sample tests including the assumption of beta-binomial distribution. The direct inclusion of the assay sensitivity, i.e.…”
mentioning
confidence: 99%