Analysis of the mechanism underlying diabetic wound healing acceleration by Calycosin-7-glycoside using network pharmacology and molecular docking

Chen, Jia; Ma, Huike; Meng, Yukun; Liu, Qingwu; Wang, Yan; Yang, Lin; Yang, Danyang; Yao, Wentao; Wang, Yazhuo; Li, Ping

doi:10.1016/j.phymed.2023.154773

Cited by 9 publications

(1 citation statement)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Calycosin-7-glucoside (CG) is an isoflavone component found in Astragalus membranaceus (AR), commonly known as Huangqi. Chen J. et al (2023) investigated the mechanism of CG in treating diabetic wounds by using a diabetic wound model and an LPS- and IFN-γ-induced inflammation model in RAW264.7 cells. The study results showed that CG accelerated wound healing and promoted granulation tissue regeneration in diabetic mice.…”

Section: Application Of Ros-scavenging Materials In Wound Healingmentioning

confidence: 99%

ROS-scavenging materials for skin wound healing: advancements and applications

Dong,

Wang

2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

The intricate healing process of skin wounds includes a variety of cellular and molecular events. Wound healing heavily relies on reactive oxygen species (ROS), which are essential for controlling various processes, including inflammation, cell growth, angiogenesis, granulation, and the formation of extracellular matrix. Nevertheless, an overabundance of reactive oxygen species (ROS) caused by extended oxidative pressure may result in the postponement or failure of wound healing. It is crucial to comprehend the function of reactive oxygen species (ROS) and create biomaterials that efficiently eliminate ROS to enhance the healing process of skin wounds. In this study, a thorough examination is presented on the role of reactive oxygen species (ROS) in the process of wound healing, along with an exploration of the existing knowledge regarding biomaterials employed for ROS elimination. In addition, the article covers different techniques and substances used in the management of skin wound. The future prospects and clinical applications of enhanced biomaterials are also emphasized, highlighting the potential of biomaterials that scavenge active oxygen to promote skin repair. This article seeks to enhance the understanding of the complex processes of ROS in the healing of wounds and the application of ROS-scavenging materials. Its objective is to create novel strategies for effective treatment skin wounds.

show abstract

Section: Application Of Ros-scavenging Materials In Wound Healingmentioning

confidence: 99%