Analysis of the Prevalence and Incidence of Cleft Lip and Palate in Colombia

Reina, Herney Alonso Rengifo; Brigetty, Guarnizo Peralta Stefany

doi:10.1177/1055665619886455

Cited by 28 publications

(19 citation statements)

References 22 publications

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“…For example, an analysis of cleft lip and palate in Colombia showed that the prevalence was 3.27 per 10 000 inhabitants from 2009 to 2017. 25 Also, the prevalence of the disease in Brazil was about 5.2/10 000. 26 Compared with some cities in our country, we found that the prevalence of cleft lip and/ or palate in Guangdong province was lower than that in Beijing (18.9/10 000) 9 and Gansu province (13.48/10 000).…”

Section: Discussionmentioning

confidence: 99%

“…28 For example, the prevalence was relatively high in East Asia and the pacific compared with other regions in the world. 25 In addition, the prevalence of the disease was unevenly distributed in different regions and/or ethnic groups in a single country, such as the heterogeneity of different regions in Georgia. 28 According to the WHO, the prevalence of birth defects in the Netherlands varied greatly.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

et al. 2021

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ObjectivesThis study aimed to investigate the temporal and spatial characteristics of cleft lip and/or palate based on a large-scale birth defect monitoring database.MethodsData on perinatal infants and children with cleft lip and/or palate defects from 1 January 2015 to 31 December 2018 in Guangdong province of China were collected. The variables including the demographic data, basic family information (address, education level, etc.), the infant’s birth weight, gender and other basic parameters were collected and analysed.ResultsDuring the study period, the prevalence of cleft lip and/or palate was 7.55 per 10 000 perinatal infants. The prevalence of cleft lip, cleft palate and cleft lip and palate were 2.34/10 000, 2.22/10 000 and 2.98/10 000, respectively. The prevalence of cleft lip and/or palate showed a pronounced downward trend, reducing from 8.47/10 000 in 2015 to 6.51/10 000 in 2018. We observed spatial heterogeneity of prevalence of cleft lip and/or palate across the study period in Guangdong. In the Pearl River Delta region, the overall prevalence of cleft lip and/or palate was 7.31/10 000, while the figure (7.86/10 000) was slightly higher in the non-Pearl River Delta region (p<0.05). Concerning infant gender, the prevalence was in general higher in boys than girls (p<0.05). In addition, the higher prevalence was more common in mothers older than 35 years old. For the birth season, infants born in spring tended to have a higher prevalence than those born in other seasons, regardless of the prevalence of cleft lip and palate calculated separately or jointly (p<0.05). The majority of newborns with cleft lip and palate were accompanied by other birth defects.ConclusionThis study contributes a better understanding of the characteristics of spatio-temporal trends for birth defects of cleft lip and/or palate in south China.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

et al. 2021

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“…In CL, this developmental abnormality occur due to the failure of the merging of the maxillary and medial nasal elevation due to inadequate migration of neural crest cells at 5 weeks’ gestational age. In CP, failure of the fusion of lateral palatine processes occurs to meet and fuse with each other (Stocum, 2001; MERRITT, 2005; Alonso & Brigetty, 2020). Fusion of palatal shelves begins at 8 weeks’ gestation and continuous usually until 12 weeks’ gestation (Bernheim et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Clinical and Demographical Characteristics of Cleft Lip and/or Palate in the Northwest of Iran: An Analysis of 1500 Patients

Galeh

Nouri‐Vaskeh

Alipour

et al. 2020

The Cleft Palate Craniofacial Journal

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Objective: Orofacial clefts (OFCs) can occur as an isolated defect or as a manifestation of other syndromes. The current study aimed to evaluate demographic characteristics and distribution of different types of accompanying anomalies for OFCs in the northwest of Iran. Design: A retrospective cohort study. Setting: Tertiary pediatric hospital. Patients and Participants: This study was conducted on 1500 cleft lip and/or palate patients born between July 2010 and June 2020 in the northwest of Iran. Main Outcome Measures: Demographic and clinical characteristics of the children with OFCs including familial history, accompanying anomalies and syndromes, maternal passive smoking, mothers’ and fathers’ age, consanguineous marriage, and birth order. Results: Among 1500 patients, 441 had cleft lip, 615 had cleft palate, and 444 had cleft lip and palate. The positive family history of OFCs was found to be 20.9% to 25.4% depending on the cleft type. Accompanying anomalies were identified in 29.8% of cases. Cardiac, facial, and ear abnormalities were the most common types. Also, 2.9% were identified with syndromes and sequences. These included Pierre Robin Sequence, Velo-cardio-facial syndrome, and Down syndrome most frequently. Conclusion: These findings may provide references for appropriate resources to establish and direct counseling and primary preventive projects in the northwest of Iran.

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“…The incidence of OFC has been described in epidemiological studies for many populations. [61][62][63][64][65][66][67] Time-series analysis techniques have been used to evaluate the change in OFC incidence in Slovenia over a 26-year period, with unexplained observation of cycling and clustering of cases. 68 Examples of ecological timeseries to evaluate the association of environmental exposures and health outcomes have most commonly been performed in the field of air pollution and mortality, where daily data is publicly available.…”

Section: Strengths and Weaknesses Of The Studymentioning

confidence: 99%

The impact of changing smoking habits and smoke-free legislation on orofacial cleft incidence in the United Kingdom: evidence from two time-series studies

Fell

Russell

Medina

et al. 2021

Preprint

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Objectives: To analyse the association between active and passive cigarette smoking and the incidence of children born with a cleft lip and/or palate within the United Kingdom. Design: First, a longitudinal time-series study was conducted with routinely collected smoking prevalence data for females over 16 years of age. Second, an interrupted time-series design was used as a natural experiment to assess the impact of smoke-free legislation using segmented Poisson regression. Setting: United Kingdom. Population: All children born between 2000 and 2018 and their mothers. Main outcome measures: Orofacial cleft incidence, reported annually for England, Wales and Northern Ireland and separately for Scotland. Results: Over the study period, the annual incidence of orofacial cleft per 10,000 live births ranged from 14.2-16.2 in England, Wales and Northern Ireland and 13.4-18.8 in Scotland. The proportion of active smokers amongst females in the United Kingdom declined by 37% during the study period. Adjusted regression analysis did not show a correlation between the proportion of active smokers and orofacial cleft incidence in either dataset, although we were unable to exclude a modest effect of the magnitude seen in individual-level observational studies. The data in England, Wales and Northern Ireland suggested an 8% reduction in orofacial cleft incidence (95%CI 1% to 14%; P=0.026) following the implementation of smoke-free legislation. In Scotland, there was weak evidence for an increase in orofacial cleft incidence following smoke-free legislation. Conclusion: These two ecological studies offer a novel insight into the influence of smoking in orofacial cleft aetiology, adding to the evidence base from individual-level studies. Our results suggest that smoke-free legislation may have reduced orofacial cleft incidence in England, Wales and Northern Ireland.

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Analysis of the Prevalence and Incidence of Cleft Lip and Palate in Colombia

Cited by 28 publications

References 22 publications

Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis

Clinical and Demographical Characteristics of Cleft Lip and/or Palate in the Northwest of Iran: An Analysis of 1500 Patients

The impact of changing smoking habits and smoke-free legislation on orofacial cleft incidence in the United Kingdom: evidence from two time-series studies

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