“…Depleted levels of 25(OH)D in the body of a pregnant woman contribute to an increase in the incidence of health complications, not only in the mother but also in newborns [ 11 , 80 , 81 ], including from pre-eclamptic mothers [ 50 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 ]. Study shows more than half of the children born prematurely have 25(OH)D deficiency (less than 20 ng/mL) [ 94 ]. The protective effect of 25(OH)D has been demonstrated in a study by Vasilyeva et al, 2017, showing a reduction in adverse neonatal outcomes such as fetal growth retardation, hypoxia, fetal cerebral injury, and 25(OH)D deficiency with 25(OH)D supplementation at a concentration of 4000 IU/day [ 95 ].…”