Analytical applications of hydrazones

Variation in the biomolecular interactions of nickel(ii) hydrazone complexes upon tuning the hydrazide fragment

“…Various important properties of carbonic acid hydrazides, along with their applications in medicine and analytical chemistry, have led to increased interest in their complexation characteristics with transition metal ions. 17 The hydrazone unit offers a number of attractive features such as the degree of rigidity, a conjugated π-system and an NH unit that readily participates in hydrogen bonding and may be a site of protonation-deprotonation. It is well established that the formation of metal complexes plays an important role to enhance the biological activity of free hydrazones.…”

Synthesis and Spectral Characterization of Hydrazone Schiff Bases Derived from 2,4-Dinitrophenylhydrazine. Crystal Structure of Salicylaldehyde-2,4-Dinitrophenylhydrazone

“…This activity is attributed to the formation of stable chelate complexes with transition metals which catalyze physiological processes [10 -12]. They also act as herbicides, insecticides, nematocides, rodenticides, plant growth regulators, sterilants for houseflies, among other applications [10,11,13]. In analytical chemistry hydrazones find applications as multidentate ligands for transition metals in colorimetric or fluorimetric determinations [14,15].…”

Simultaneous Second Order Derivative Spectrophotometric Determination Of Gallium (III) and Aluminium(III) using Diacetylmonoxime IsonicotinoylHydrazone

“…Many of physically active hydrazones find application 1 in the treatment of diseases like tuberculosis, leprosy and mental disorders. Hydrazones also act as herbicides, nematocides, rodenticides, plant growth regulators, anti microbial, anti tuberculosis and anti tumor activities 2,3 . Hydrazones act as chelating agents by forming colored complexes with metal ions.…”