Analytical characteristics of a commercial ICP orthogonal acceleration time-of-flight mass spectrometer (ICP-TOFMS)

Abstract

NRC Publications Record / Notice d'Archives des publications de CNRC:http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8899217&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8899217&lang=fr READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1039/b000496kJournal of Analytical Atomic Spectrometry, 15, 6, pp. 607-616, 2000 Full PaperAnalytical characteristics of a commercial ICP orthogonal acceleration time-of-¯ight mass spectrometer (ICP-TOFMS){ Analytical data illustrating the typical response characteristics of a commercial inductively coupled plasma orthogonal acceleration time-of-¯ight mass spectrometer (Optimass8000 ICP-oa-TOFMS, GBC Scienti®c Equipment Pty Ltd., Australia) are presented. With optimum instrument response tuned at mid-mass ( 103 Rh), limits of detection for a suite of elements representative of m/z 9±238 were estimated to be typically 1 ppt; background counts across the mass range averaged 0.5 Hz; sensitivity was 7 MHz per mgml 21 (Rh); resolution (FWHM) ranged from 500 ( 7 Li) to 2200 ( 238 U); long-term drift over 700 min was 0.7% h 21 ; abundance sensitivity was 2.8610 26 (low mass side) and 7.4610 25 (high mass side); mass bias ranged from 10% per u at 24 Mg to v1% per u at m/zw80 and isotope ratio precision was demonstrated to be limited by counting statistics when the detector was operated in the pulse counting mode. Matrix effects, while relatively insigni®cant at 30 ppm NaCl and reaching 60±80% suppression of response at 3500 ppm, had no in¯uence on the measured resolution, mass calibration or isotope ratio accuracy. The instrument faithfully recorded transient signals arising from¯ow injection sample introduction, from which isotope ratio information free of time skew could be generated.

An Overview of Analytical Applications of Time of Flight-Mass Spectrometric (TOF-MS) Analyzers and an Inductively Coupled Plasma-TOF-MS Technique

“…155 The resolving power decreases towards low masses being, however, considerably higher than that observed for quadrupole systems. A resolution >415 at 10% peak hight for Pb and Bi (100 ng ml -1 ) using the LECO Renaissance instrument was reported.…”

“…A detailed summary of those instruments is available. 154 Analytical characteristics of an orthogonal 155 and of an-axial ICP-TOF-MS 156,157 instruments have been presented.…”

Inductively Coupled Plasma Zoom–Time-of-Flight Mass Spectrometry

“…Commercial single-reflectron ICP-TOFMS systems routinely produce mass resolution on the order of 1000-2500 for up to 1-m flight paths [36,37]. The current 35-cm geometry ICP-zoom-TOFMS system performs well within that resolution range for both operational modes.…”

“…The calculated detection limit (by Figure 3. (a) CEA-and (b) CMA-TOFMS mass spectra for lead that correspond to the data in Table 1. The baseline fluctuations in both traces are due to an impedance mismatch in the detection system that causes ringing [36,37,39]. However, when the zoom-TOFMS instrument is operated in the CMA zoom mode at a 43.5 kHz repetition rate, the LDR of the instrument is expanded.…”

Detection of Bromine by ICP-oa-ToF-MS Following Photochemical Vapor Generation

“…Optimization and mass calibration of the ICPoa-ToF-MS was undertaken using solution nebulization sample introduction with 200 ng/mL feed solutions of Br − or BrO 3 − as well as a mixed 10 ng/mL multielement tuning solution, as described by Sturgeon et al 28 With mass spectrometer parameters optimized, generation of volatile bromide species was undertaken using the PVG reactor, and experimental conditions yielding maximum response and stability were identified, including solution matrix composition and irradiation time (flow rate through the PVG reactor) as well as Ar gas transfer flow rate through the GLS. Once established, calibration functions were derived and limits of detection Relative response from Br − or BrO 3 − was noted for both solution nebulization and PVG sample introduction under optimum conditions of each.…”