Analytical functions for beta and gamma absorbed fractions of iodine-131 in spherical and ellipsoidal volumes

Abstract

The analytical functions that we obtained from fitting process in Monte Carlo data can be used for obtaining the absorbed fractions of iodine-131 beta and gamma rays for any volume of the thyroid lobe. Moreover, our results for the spheres are in good agreement with the results of MIRD and other scientific literatures.

Radionuclide Imaging-Guided Chemo-Radioisotope Synergistic Therapy Using a 131I-Labeled Polydopamine Multifunctional Nanocarrier

“…The drug release behavior of PDA-PEG-SAN-MET nanoparticles was determined at different pH (5.3 or 7.4) and accelerated drug release was found at low pH due to the positive charge of SAN or MET (Figures 3C and 3D). Since 131 I can emit strong both b and g rays, 24 131 I is not only particularly used for radiotherapy, but also used as a contrast agent for gamma imaging. To achieve imaging-guided internal radiotherapy, 131 I was utilized to label PDA-PEG via electrophilic substitution reaction in the presence of iodogen.…”

Is a single late SPECT/CT based kidney 177Lu-dosimetry superior to hybrid dosimetry with sequential multiple time-point whole-body planar scans in combination with an early SPECT/CT?

“…The imaging-protocol C based simplified dosimetry approach refers to equation (1) [33] where r S is the tissue under investigation, D(r S ) is the total absorbed dose to r S by self-irradiation, A(r S ,t) is the accumulated activity in r S as a function of time after the administration, and S(r S ← r S ) is the absorbed dose per decay or the dose rate per unit activity. The beta energy per decay imparted by 177 Lu emitted by beta emissions within the organ is almost independent of the size and shape of the organ due to the short range of the electrons [34,35]. In this study, we only perform mean organ-based dosimetry, potential variations of the spatial and temporal activity distribution in the organ are not directly considered.…”