Analytical Methods for Volatile Methylsiloxanes Quantification: Current Trends and Challenges

Seasonal and latitudinal variability in the atmospheric concentrations of cyclic volatile methyl siloxanes in the Northern Hemisphere

“…31 Quality assurance/quality control Atmospheric monitoring of cVMS is well-known for its susceptibility to both analyte loss from, and contamination of, the sample during sample collection, processing, and analysis. 25,26 When sampling in remote locations, the risk of contamination compromising the measurement increases because concentrations are low and transport of samples to and from the sampling site can be long and complex. Several measures were adopted to minimize and monitor contamination.…”

“…20 A second explanation could be design features and quality control protocols that do not reliably prevent sample contamination, which is a major concern with cVMS analysis. 25,26 The procedure for preparing SIPs by coating foam disks with ground XAD-powder is highly susceptible to sorbent contamination. Furthermore, a methylsiloxane-based silicone surfactant may be used as a processing aid in PUF manufacturing, 27 and the polymeric siloxane residuals are not readily removed by washing.…”

Progress in research on the safety of silicone rubber products in food processing

“…Meanwhile, Krenczkowska et al (2019) discovered an increase in siloxane levels in the epidermis in the order D4, D6, D5, with an average of D4-6.36, D5-29.23, and D6-10.75 g/cm 2 /24 h. This implied that the ability to permeate from the stratum corneum to the epidermis was related to the interlayer concentration gradient, as well as the cyclic siloxane's molecular weight and lipophilicity, as a result of a synergistic effect of factors. Homem and Ratola (2020) hypothesized that because of their relatively high bioaccumulation potential, they interfere with the female reproductive system, liver, and lungs, as well as irritate the skin, eyes, and respiratory system. The stratum corneum, epidermis, and dermis are also potential reservoirs for cyclic siloxane oligomers, which are then absorbed into the bloodstream in a long and uncontrolled process.…”

Advances in the Separation and Detection of Secondary Organic Aerosol Produced by Decamethylcyclopentasiloxane (D5) in Laboratory-Generated and Ambient Aerosol

“…1−4 Approximately 2.1 million tons of silicone-containing goods were produced in 2013 of which 17% (357000 tons) were personal care and consumer products. 3 The VMS in PCPs includes hexamethylcyclotrisiloxane (D 3 ), octamethylcyclotetrasiloxane (D 4 ), decamethylcyclopentasiloxane (D 5 ), dodecamethylcyclohexasiloxane (D 6 ), hexamethyldisiloxane (L 2 ), octamethyltrisiloxane (L 3 ), decamethyltetrasiloxane (L 4 ), and dodecamethylpentasiloxane (L 5 ). 5,6 D 5 has been reported as the predominant VMS in personal care products and in the environment.…”