Anaplastic carcinoma of the lung with metastasis to the anus

Metastatic primary peritoneal carcinoma: an unexpected finding on histological examination of haemorrhoids

“…Although uncommon, anal metastasis from colonic cancer is well described. Nongastrointestinal cancers metastasizing to the anus are exceptionally rare, with the only reports in the literature comprising two squamous and one anaplastic lung carcinoma, a lobular breast carcinoma and a renal‐cell carcinoma [1–4].…”

Perianal Metastasis of Non-Small Cell Lung Cancer

“…ND -CK7: cytokeratin 7, CK20: cytokeratin 20, EMA: epithelial membrane antigen, TTF-1: thyroid transcription factor-1, AFP: alpha fetoprotein, GCDFP-15: gross cystic disease fluid protein-15, ND: not done reported in the literature (1)(2)(3)(4)(5). Of these cases, two involved squamous cell carcinoma, one involved adenocarcinoma, one involved mucoepidermoid carcinoma and one involved anaplastic cell carcinoma.…”

“…Perianal and anal metastases originating from primary lung cancer are extremely rare, with only a few cases having been reported in the literature (1)(2)(3)(4)(5). We herein report the case of a 36-year-old woman who developed perianal metastasis of a non-small cell lung cancer (NSCLC) that presented with symptoms mimicking a hemorrhoid.…”

Poorly differentiated tumours of the anal canal: a diagnostic strategy for the surgical pathologist

“…Metastatic lesions to the anal canal are most often from a colorectal primary 58–60 . Metastases from other sites are exceedingly rare, with a wide spectrum of primary locations 61–64 . However, the majority of these non‐colorectal metastases to the anus were not poorly differentiated neoplasms and displayed various histological features suggestive of a metastasis from another site.…”

“…[58][59][60] Metastases from other sites are exceedingly rare, with a wide spectrum of primary locations. [61][62][63][64] However, the majority of these noncolorectal metastases to the anus were not poorly differentiated neoplasms and displayed various histological features suggestive of a metastasis from another site. In the single report of a poorly differentiated carcinoma metastasizing to the anus, there was documented evidence of a pre-existing lung primary.…”