Anatomical and functional evaluation of tympanoplasty using a transitory natural latex biomembrane implant from the rubber tree Hevea brasiliensis

Abstract

PURPOSE: To compare the role of transitory latex and sylastic® implants in tympanoplasty on the closure of tympanic perforations. METHODS: A randomized double-blind prospective study was conducted on 107 patients with chronic otitis media submitted to underlay tympanoplasty and divided at random into three groups: control with no transitory implant, latex membrane group, and sylastic® membrane group. RESULTS: Greater graft vascularization occurred in the latex membrane group (p<0.05). Good biocompatibility was obtained with the use of the latex and silicone implants, with no effect on the occurrence of infection, otorrhea or otorragy. CONCLUSION: The use of a transitory latex implant induced greater graft vascularization, with a biocompatible interaction with the tissue of the human tympanic membrane.

Development and testing of an absorbable spring for cranial expansion in rabbits

“…8 shows marked peri-implant neovascularization. Similar findings have been reported in other tissues in experiments using latex (Araujo et al, 2012). As shown by the absence of infection and the minor inflammatory reaction, the tested blend is highly biocompatible and bioadaptable (Araujo et al, 2012).…”

Evaluation of wound healing treated with latex derived from rubber trees and Aloe Vera extract in rats

“…Thus, it suggests the performance of mannose-6-fosfate as a substrate for fibroblasts and, therefore, for collagen organized structuring and wound contracture. It was also observed in rat wounds and burns 3 . In addition, it was not detected any bacterial colony in the crust at 7 days in this group, which may infer the antibacterial and antifungal activity of anthraquinones present in this extract 5 .…”

In Situ Characterization of Micro-Vibration in Natural Latex Membrane Resembling Tympanic Membrane Functionally Using Optical Doppler Tomography

“…In this study, we used a natural latex membrane to approximate the condition with the human TM for detecting micro-vibrations on a sample surface [58,59]. However, due to differences of natural parameters like thickness and elasticity between the latex membrane and the TM, the limitations about creating a complex vibratory motion on the latex were remained.…”