Anatomical and histological changes of uterine horn of Aceh cattle with repeat breeding

Thasmi, Cut Nila; Siregar, Tongku Nizwan; Wahyuni, Sri; Aliza, Dwinna; Panjaitan, Budianto; Nazaruddin, Nazaruddin; Fallatanza, Miranda

doi:10.5455/javar.2018.e297

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…Receptive endometrium is vital for appropriate fetal-maternal communication to establish a successful pregnancy. Bovine endometrium, based on its structure and function, is divided into two layers, namely the basal layer and the functional layer with pseudostratified columnar/simple columnar epithelial cells [ 21 ]. The endometrium undergoes morphological and functional changes throughout the estrous cycle to receive a viable competent blastocyst [ 22 ] and remains under the influence of ovarian hormones (estradiol-17β and progesterone).…”

Section: Proteomics Of Bovine Uterus Milieu To Decipher the Molecular...mentioning

confidence: 99%

Proteomic Approaches to Unravel the Molecular Dynamics of Early Pregnancy in Farm Animals: An In-Depth Review

Jamwal,

Jena,

Tyagi

et al. 2023

JDB

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Infertility is a major problem in farm animals, which has a negative economic effect on farm industries. Infertility can be defined as the inability of animals to achieve a successful pregnancy. Early pregnancy is crucial to establish a successful pregnancy, and it is reported that 70–80% and 20–30% of total embryonic loss occur in cattle and pigs, respectively, during the first month of pregnancy. The advanced high-throughput proteomics techniques provide valuable tools for in-depth understanding of the implantation process in farm animals. In the present review, our goal was to compile, assess, and integrate the latest proteomic research on farm animals, specifically focused on female reproduction, which involves endometrial tissues, uterine fluids, oviductal fluids, and microRNAs. The series of studies has provided in-depth insights into the events of the implantation process by unfolding the molecular landscape of the uterine tract. The discussed data are related to pregnant vs. non-pregnant animals, pregnancy vs. oestrous cycle, different days of the early pregnancy phase, and animals with uterine infections affecting reproduction health. Some of the studies have utilized non-invasive methods and in vitro models to decipher the molecular events of embryo-maternal interaction. The proteomics data are valuable sources for discovering biomarkers for infertility in ruminants and new regulatory pathways governing embryo-uterine interaction, endometrium receptivity, and embryonic development. Here, we envisage that the identified protein signatures can serve as potential therapeutic targets and biomarkers to develop new therapeutics against pregnancy diseases.

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Section: Proteomics Of Bovine Uterus Milieu To Decipher the Molecular...mentioning

confidence: 99%

Proteomic Approaches to Unravel the Molecular Dynamics of Early Pregnancy in Farm Animals: An In-Depth Review

Jamwal,

Jena,

Tyagi

et al. 2023

JDB

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“…Histopathology and culture sensitivity are the major tools to evaluate reproductive issues and infertility. Histopathology better describes the status of endometrial glands, caruncles, inflammatory cell infiltration, hemorrhages, and the thickness of uterine layers (Thasmi et al 2018). Currently, the problem is a limitation of knowledge about the cause of repeat breeding and infertility in buffalo.…”

Section: Introductionmentioning

confidence: 99%

Histopathological Changes in the Uterus of Infertile Slaughtered Buffaloes

huq

Channa

Yousaf

et al. 2023

PJS

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Agribusiness is the foundation of Pakistan's economy as it contributes 18.9 percentto the nation's GDP. Buffalo is a significant investor with a populace of 38.8 million heads. Theprofitable characteristics of Nili Ravi wild ox are inimitable with some other buffalo breeds on theplanet, while the conceptive qualities are still nadir. The most widely recognized regenerative issuesexperienced are postponed time of pubescence, helpless estrus articulation, low ripeness with AI,deferred baby blues anestrous, and irregularity. These attributes have made it amazingly hard toincrease quick hereditary advancement in this variety. Conceptive biotechnologies assume a key job inbreed improvement by bypassing these obstacles. For this study eighty animals were selected andslaughtered due to reproductive issues and reproductive tracts were collected from the slaughterhouseand observe the tract grossly (texture and shape, any exudate, ovarian structures). Then cut the uterinetissue sample with the size of 2 × 2 × 2cm was fixed in formalin 10% for histopathology. Afterprocessing microscopy was performed to find histopathologic changes (Endometrial epithelium,uterine gland, and inflammatory cells and caruncles status). The grading of animals is labeled asNormal (-), Mild (+), Moderate (++), and Severe (+++) on basis of the degree of infection. The whiteside test was negative for 40% of samples while 60% of animals are positive with different degrees ofaffection. Endometrial epithelium erosion is absent in 31.43% of animals while 68.67% of animalshave erosions. Atrophy of uterine glands was absent in 41.43% of animals while 58.67% of animalscontained atrophy of glands. 11.43% of animals were negative for inflammatory cells while 88.66% ofanimals were positive for inflammatory cells. 20% of animals had normal caruncles while 80% ofanimals had swelled caruncles. Discharge was collected for the white side test from the cervix. 62.86%of animals had serious discharge while 37.14% of animals had a purulent discharge. The color andtexture of the tract are divided into two categories pale and pale reddish with swelling. 54.74% had apale color while 45.26% had a pale and reddish with swelling. In conclusion, 60% of animals wereaffected by endometritis including mild, moderate, and severe. Histopathological parameters and thenature of exudate also showed a significant relationship with endometritis which was indicated by thewhite side test. The treatment of endometritis should be done after the white side test beforeinsemination. In this way, we can improve reproductive performance and conception rate. Furtherstudies are warranted to perform the culture sensitivity test and treat the animals with intra-uterine andsystemic antibiotic therapy.

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“…This causes subclinical endometritis, which consequently results in fertilization or implantation failure. Thasmi et al (2018) reported the changes in anatomy pathology and histopathology of repeat breeding Aceh cows with endometritis caused by subacute and chronic infections. Various therapies have been applied for repeat breeding cows due to endometritis, including the use of antibiotics and prostaglandins (Drillich, 2006;Hussain et al, 2013;Ahmed and Elsheikh, 2014;Mido et al, 2016;and Szenci, 2016).…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Lugol on the Increasing of Pregnancy Rate in Aceh Cow with Endometritis

et al. 2021

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ABSTRACT. The objective of this study was to determine the effect of lugol on the increasing the pregnancy rate in repeat breeding (RB) Aceh cows due to endometritis. This study used six endometritis’s cows, aged 5-7 years, weighed 150-250 kg which were divided into two groups (n=3), KI and KII. The cows in group 1 (K1) were injected with 5 ml PGF2α, while the cows in group 2 (KII) were treated with 50 ml of 2% lugol intra-uterine and continued with an injection of 5 ml PGF2α after healing. The detection of estrus was performed twice a day following by artificial insemination (AI) about 10-16 hours after the onset of estrus. Determination of pregnancy was performed by ultrasonography (USG) on the 25th day after AI. The data obtained were analyzed descriptively. The results showed that all endometritis ’cows in KI and KII present estrous signs (100%). However, only one cow was recovered in K2, whereas in K1 did not. After AI, one pregnant cow was observed in KII (33.3%), while none of the pregnant cows was found in K1 (0.0%). It is concluded that the lugol treatment for endometritis’s Aceh cows can improve the pregnancy rate. (Efektivitas larutan lugol untuk meningkatkan persentase kebuntingan pada sapi Aceh yang mengalami endometritis) ABSTRAK. Penelitian ini bertujuan mengetahui pengaruh pemberian larutan lugol terhadap peningkatan persentase kebuntingan sapi Aceh yang mengalami RB. Dalam penelitian ini digunakan enam ekor sapi Aceh betina dewasa, umur 5-7 tahun, bobot badan 150-250 kg, sudah pernah beranak, dan didiagnosis mengalami endometritis. Seluruh sapi dibagi menjadi dua kelompok (n=3). Pada kelompok 1 (K1), sapi endometritis diterapi dengan 50 ml lugol 2% secara intra uteri dan setelah sembuh dilanjutkan dengan penyuntikan 5 ml PGF2α. Sapi pada kelompok 2 (K2) hanya diinjeksi dengan 5 ml PGF2α. Deteksi berahi dilakukan sebanyak dua kali per hari dan inseminasi buatan (IB) dilakukan sekitar 10-16 jam setelah awal berahi. Pemeriksaan kebuntingan dilakukan dengan ultrasonografi (USG) pada hari ke-25 setelah IB. Data dianalisis secara deskriptif. Dari masing-masing kelompok, hanya satu ekor sapi pada K2 yang dinyatakan sembuh yaitu sapi pada kelompok kedua. Persentase sapi yang menjadi estrus pada kedua kelompok masing-masing adalah 100%. Dari tiga ekor sapi yang diinseminasi pada masing-masing kelompok, hanya satu ekor sapi pada K2 (33,3%) yang menunjukkan hasil positif bunting sedangkan pada K1 tidak terdapat sapi yang menunjukkan hasil positif (0,0%). Disimpulkan bahwa pemberian larutan lugol pada sapi Aceh yang mengalami endometritis dapat meningkatkan persentase kebuntingan sapi Aceh.

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Anatomical and histological changes of uterine horn of Aceh cattle with repeat breeding

Cited by 6 publications

References 10 publications

Proteomic Approaches to Unravel the Molecular Dynamics of Early Pregnancy in Farm Animals: An In-Depth Review

Proteomic Approaches to Unravel the Molecular Dynamics of Early Pregnancy in Farm Animals: An In-Depth Review

Histopathological Changes in the Uterus of Infertile Slaughtered Buffaloes

The Effectiveness of Lugol on the Increasing of Pregnancy Rate in Aceh Cow with Endometritis

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