Anatomical structures determining blood flow in the heart left ventricle

Abstract

The presence of twisted helical flow patterns in the cardiac cavities during ventricular filling and ejection was supposed. This work was intended in order to show that the intraventricular trabeculation plays the determining role in such a flow formation and to find some analytical approaches for its analysis. The morphometric study of human left-ventricular and aortic corrosion casts and dynamic measurement of the aorta by MRI-technique were performed. The data were analysed by means of the "Mathematica'" program. Two groups of trabecules were identified that refer to the inlet and outlet of the ventricular blood flow. The first group consists of trabecules of the free left-ventricular wall. The second group consists of long trabecules going along the anterior left-ventricular wall and intracavital lines of the papillary muscles. Both are twisted clockwise and converge in the flow direction. Each group of trabecules is oriented towards the mitral or aortic valve orifices, correspondingly. It was concluded that the helical trabecular organization acts as flow directing paddles that change their mutual orientation during the cardiac cycle evolution. The reorientation of the flow takes place due to sequential contraction of the ventricular structures. The formalization of trabecular orientation will allow one to calculate improved models of implantable substitutes and auxiliary devices for cardio-vascular surgery.

MRI myocardial motion and fiber tracking: a confirmation of knowledge from different imaging modalities

“…For hemodynamic comparison, phasic records of ultrasonic crystal recordings were reviewed that displayed the standard motion findings in these four phases of isometric contraction, ejection, rapid filling in the isovolumic phase, and mid-diastole [5], together with data obtained by echocardiography (methods described below) and recently reported radionuclide ventriculography findings by BallesterRodes et al [6]. There is also correlation of MRI-described motion with morphologic data about how the trabecular arrangements of spiral ventricular fibers compress underlying blood, and how ventricular musculature effects blood flow, using corrosion cast analyses [8].…”

Septal structure and function relationships parallel the left ventricular free wall ascending and descending segments of the helical heart

“…Recent studies by Gorodkov et al [22] used ventricular corrosion casts to display how spiral fibers compressed blood to provide further confirmation of oblique trabeculae. Additionally, MRI analysis of strain and velocity by Jung et al [23] defined an oblique systolic shortening velocity, together with a similar reciprocal acceleration velocity during ejection, as a functional supplement to septal oblique fiber orientation.…”

Tenth RESTORE Group Meeting: overview

“…Fig. 2 displays the interaction between descending segment geometry from the normal heart model, MRI evidence of acceleration tracts from velocity curves from Jung et al [13] at Freiburg, Germany and by corrosion casts by Gorodkov et al [14] at the Bakoulev Scientific Institute in Moscow that define how the spiral ventricular muscle trabeculae compress blood in the cavity.…”