Anchoring Dental Implant in Tissue-Engineered Bone Using Composite Scaffold: A Preliminary Study in Nude Mouse Model

Synthetic and Marine-Derived Porous Bone Graft Substitutes

“…Also, dental implants were fixed in the newly formed bone and surrounding the implant new bone was formed. On the other hand, no bone formation was observed in the control scaffold [154].…”

“…In a different approach, Chen et al [154] inserted a titanium dental implant into a coral scaffold seeded with BMSCs and, then, implanted subcutaneously into nude mice back. Defects treated with coral carrying no cells were used as an experimental control.…”

Biomaterials from beer manufacture waste for bone growth scaffolds

“…To study cell adhesion to the materials, the biocompatibility and efficiency for bone growth, MC3T3-E1, an osteoblast-like cell line, was chosen because they are well characterized for modeling endogenous osteoblasts (16). A commercial synthetic scaffold, hydroxyapatite nanopowder (B200 nm) from Sigma Aldrich, was used for comparison.…”

“…For example, coral has been found to be an interesting natural substitute; according to the investigators, ''the tissue-engineered bone of seeded natural coral-implant composite scaffold is promising for dental implant anchoring, which has positive implication for clinical jaw reconstruction'' (15). However, this material is non-renewable, and its use can seriously damage the local environment, both flora and fauna, from whence it is removed (16).…”

Sustainable Materials and Biorefinery Chemicals from Agriwastes

“…To study cell adhesion to the materials, their biocompatibility and efficiency for bone growth, MC3T3-E1, an osteoblast-like cell line, was chosen because they are well characterised for modelling endogenous osteoblasts [47]. A commercial synthetic scaffold, hydroxyapatite (HA) nanopowder (B200 nm) from Sigma Aldrich, was used for comparison purposes.…”