2013
DOI: 10.4317/jced.50950
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Ancient Schwannoma of the hard palate. An uncommon case report and review

Abstract: Schwannoma or neurilemmoma is an infrequent benign tumor in the oral cavity that originates from the Schwann cells on the neural sheath of the peripheral nerves. Schwannomas are frequently located in the soft tissues of head and neck region, but only a 1 to 12% of them are located in the oral cavity. Some histological variants of schwannoma have been described including the cellular, plexiform, epithelioid, ancient, and melanocytic types. The “ancient schwannoma” is an uncommon variant of this tumor that shows… Show more

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Cited by 28 publications
(38 citation statements)
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“…Histopathologically, AS shows degenerative features such as hemorrhage, hemosiderin pigmentation, cellular atypia, and areas of myxoid degeneration. [ 7 ] In the present case also, all the histological features were noted accompanied by Antoni A and B cellular configuration with verocay bodies. Immunohistochemically, they are positive for S-100, Leu-7, and Myelin basic protein confirming their neural origin.…”
Section: Discussionsupporting
confidence: 71%
“…Histopathologically, AS shows degenerative features such as hemorrhage, hemosiderin pigmentation, cellular atypia, and areas of myxoid degeneration. [ 7 ] In the present case also, all the histological features were noted accompanied by Antoni A and B cellular configuration with verocay bodies. Immunohistochemically, they are positive for S-100, Leu-7, and Myelin basic protein confirming their neural origin.…”
Section: Discussionsupporting
confidence: 71%
“…Now, commonly referred to as schwannomas after the term was coined by Masson in 1932,[4] these tumors of neurogenic origin are usually benign and seldom show malignant transformation.…”
Section: Discussionmentioning
confidence: 99%
“…Schwannomas most often occur in the fourth and fifth decade of life and seem to have a 1.6:1 female predilection. 6 They have been found to be present in such varied locations as the brachial plexus and the sciatic nerve. Rarely, Schwannomas can be found in the leg or in the foot and ankle region.…”
Section: Discussionmentioning
confidence: 99%