Anemia and Transfusions in Surgical Patients: Current Concepts and Future Directions

Leichtle, Stefan W.; Mouawad, Nicolas J.; Bander, Joseph J.

doi:10.4172/2155-9864.s1-002

Cited by 2 publications

(2 citation statements)

References 63 publications

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“…In this study, we try to understand if the difference of oxygen binding capacities from various species or individuals who are habituated to live in a relatively low oxygen pressure can be reflected by the electrophoretic migration pattern of their hemoglobin (Leichtle et al 2011). We chose the hemoglobin because it is the only protein which bind directly and immediately the environmental oxygen, in air as well as soluble in water (Criner et al 2010).…”

Section: Discussionmentioning

confidence: 99%

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Comparison of Hemoglobins from Various Subjects Living in Hypoxia

Puspitaningrum

Mantolini

Rusdi

et al. 2013

HAYATI Journal of Biosciences

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The aim of this research was to obtain the different characteristics of haemoglobin molecules in subjects under hypoxic condition, namely eel, catfish, suckermouth fish, green sea turtle using an electrophoresis technique. We used human umbilical cord blood and thalassemia patient blood, as well as a normal adult-human blood as controls. The proteins obtained after electrophoresis process were stained with two different colouring techniques, each based on different principles. Both staining techniques gave practically identical results. Subject that live in hypoxic condition has a different haemoglobin in comparison to the one found in adult human live in normal oxygen condition (normoxia). These hypoxia-adapted or -needed hemoglobin migrate slower than adult human hemoglobin from normoxia. This observation suggests that hemoglobin which is needed to live in hypoxic condition or environment is a different molecule. Whether this hemoglobin from hypoxic condition has a higher affinity to oxygen is not yet known. Further study is needed to clarify this issue.

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Section: Discussionmentioning

confidence: 99%

“…It is well known that such a molecule is hemoglobin (Leichtle et al 2011). Hence, it is reasonable to think that this oxygen-binding molecule might have a different characteristic in such animals or condition.…”

Section: Introductionmentioning

confidence: 98%