Anemia in pregnancy

Diejomaoh, F. M. E.; Abdulaziz, A.; Adekile, A. D.

doi:10.1016/s0020-7292(99)00034-x

Cited by 22 publications

(25 citation statements)

References 2 publications

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“…Anemia is seen in different populations, with different etiology, incidence and severity and the most common medical disorder in pregnancy 1. Half of pregnant women are anemic worldwide 2.…”

Section: Introductionmentioning

confidence: 99%

Can anemia predict perinatal outcomes in different stages of pregnancy?

Vural¹,

Töz²,

Özcan³

et al. 2016

Pak J Med Sci

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Objective:To investigate the effect of anemia on perinatal outcomes as preterm delivery (PTD) and low birth weight (LBW) in the different stages of pregnancy.Methods:Medical records of 39,587 Turkish pregnant women who delivered between January 2011 and September 2014 were reviewed. Anemia during pregnancy was defined as hemoglobin (Hb)< 11 g/dl, low birth weight was defined as birth weight <2500 gr and PTD was defined as <37 weeks. The pregnant women were divided into three groups (Hb<10 gr/dl, Hb 10-11 gr/dl, Hb>11 gr/dl). Perinatal outcomes were compared between these anemic and non-anemic groups.Results:The anemia prevalence in our study was 25.1%. In the first and second trimester of Hb<10g/dl group LBW ratio was significantly higher (respectively 13.5%, 9.8%, p=0.03; 22.7%, 14.7%, p=0.01). In the second and third trimesters of Hb<10 g/dl group PTD ratio was significantly higher (respectively 29.1%, 19%, p=0.00; 17.7%, 15.4% p=0.02). In the first trimester Hb<10 g/dl group cesarean section rate was significantly higher (respectively 65.2%, 57.6%, p = 0.01).Conclusions:LBW infants and preterm birth rate was higher in Hb <10 gr/dl group than non-anemic in the first, second and third trimester. Hb <10 gr/dl group had higher cesarean rate in first trimester. The mean birth weight was significantly lower in anemic pregnant women in the second trimester. Preterm birth and cesarean section rate, in the group of anemic throughout pregnancy was higher than those of non-anemic in the whole pregnancy period.

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Section: Introductionmentioning

confidence: 99%

Can anemia predict perinatal outcomes in different stages of pregnancy?

Vural¹,

Töz²,

Özcan³

et al. 2016

Pak J Med Sci

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“…Anemia is the most common medical disorder in pregnancy and has a varied incidence, etiology and degree of severity in different populations, being more common in the developing countries [1]. In India, more than 90 % of anemia cases are estimated to be due to iron deficiency, because of largely vegetarian dietary patterns [2].…”

Section: Introductionmentioning

confidence: 99%

A Randomised Controlled Trial to Compare Intravenous Iron Sucrose and Oral Iron in Treatment of Iron Deficiency Anemia in Pregnancy

Gupta

Manaktala

Rathore

2013

Indian J Hematol Blood Transfus

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The aim of this study was to compare the efficacy and safety of intravenous iron sucrose with oral iron therapy in pregnant patients with anemia. The primary outcome of the study was increase in haemoglobin on day 7, 14 & 28 and rise of serum ferritin over 28 days. The study population consisted of 100 patients with singleton pregnancy between 24 and 34 weeks, hemoglobin levels between 7.0-9.0 gm/dL and serum ferritin levels less than 15 ng/mL. The participants in the oral group were given daily 180 mg elemental iron in three divided oral doses for 4 weeks. Total calculated dose of iron sucrose with a target hemoglobin of 11 gm %, was given in 200 mg dose on alternate days. Mean haemoglobin rise was 0.58 gm/dL in the IV group as compared to 0.23 gm/dL in the oral group on day 14 and 1.9 gm/dL in the IV group & 1.3 gm/dL in the oral group on day 28, (p <0.05). In the IV group, 76% of the subjects achieved haemoglobin levels of ≥11 gm% at the time of delivery, as compared to only 54% of the subjects in the oral group who achieved these levels. Serum ferritin value was significantly higher in the IV group, 37.45 ± 5.73 ng/mL as compared to 13.96 ± 1.88 ng/mL in the oral group at 4th week (p <0.001). There was no major side effect in the IV group. 36% subjects in the oral group developed gastrointestinal side effects & 10% of the subjects were non compliant. The rate of hemoglobin rise is faster with intravenous iron sucrose therapy as compared to oral iron therapy which can be beneficial in pregnant women presenting with anemia at a later period of gestation. Intravenous iron sucrose is very well tolerated during pregnancy.

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“…1,2 Anaemia is the most common medical disorder in pregnancy and has a varied incidence, aetiology and degree of severity in different populations. [3][4][5] The reported principal causes of anaemia in pregnancy in sub-Saharan Africa include iron and folate deficiencies, malaria, parasitic infections and, more recently, infection with the human immunodeficiency virus (HIV). 2 Anaemia in pregnancy is a major risk factor for poor pregnancy outcome.…”

Section: Introductionmentioning

confidence: 99%