Anestesia y analgesia epidural en la resección hepática: seguridad y efectividad

Esteve, N.; Ferrer, Ana; Sansaloni, C.; Mariscal, Marcial; Torres, María José; Mora, Carmen

doi:10.1016/j.redar.2016.06.006

Cited by 11 publications

(1 citation statement)

References 26 publications

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“…At present, the commonly used anesthesia method in the radical resection of lung cancer is general anesthesia combined with epidural anesthesia. The use of epidural anesthesia has an inhibitory effect on stress response, thereby maintaining hemodynamic stability, and epidural anesthesia can also reduce the use of anesthetic drugs and shorten patient's recovery time by inhibiting pain conduction (18,19). Cisatracurium besilate is a non-depolarizing muscle relaxant drug, and N-methyltetrahydropapaverine is a metabolite of the drug.…”

Section: Discussionmentioning

confidence: 99%

Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer

et al. 2019

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The effects of different doses of cisatracurium besilate on perioperative hemodynamics and early postoperative cognitive function in patients undergoing radical resection of lung cancer were investigated. One hundred and thirty-six patients who underwent radical resection of lung cancer from June 2013 to June 2016 in Dongying People's Hospital were retrospectively analyzed. Patients who were not given atracurium were selected as the control group (n=35). According to the different anesthetic doses, patients in the experimental group were separated into low dose (0.15 mg/kg cisatracurium besilate) group (LD group, n=34), medium dose (0.2 mg/kg cisatracurium besilate) group (MD group, n=36) and high dose (0.3 mg/kg cisatracurium besilate) group (HD group, n=31). The mean arterial pressure and heart rate (HR) were recorded before induction of anesthesia (T0), at the time of entering pleural cavity (T1), at the end of surgery (T2), and 1 day after surgery (T3). The Mini-Mental State Examination (MMSE) was used to evaluate the postoperative cognitive function scores of the 4 groups 1 day before operation and on the 1st, 3rd and 7th day after surgery. The agitation of patients at 6 and 12 h after operation was evaluated by Ramsay sedation score. There was no significant difference in arterial pressure among the four groups at T2 and T3 (P>0.05). There was no significant difference in terms of MMSE among the four groups 1 day before operation, 3 days after operation and 7 days after operation, but the MMSE score of the control group was significantly lower than that of the LD, MD and HD groups 1 day after surgery (P<0.05). Therefore, cisatracurium besilate can stabilize hemodynamics during radical operation of lung cancer and reduce the incidence of postoperative cognitive dysfunction, and it has no close association with the dose.

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Section: Discussionmentioning

confidence: 99%