Anesthetic Management of a Patient with Cri Du Chat Syndrome. Case Report

Abstract

Patients with Cri Du Chat syndrome have clinical characteristics that are very important for their anesthetic management, being the responsibility of the anesthesiologist to consider carefully the structural particularities of each patient.

Perioperative Care of a Child With Cri Du Chat Syndrome

“…Other health problems associated with CdCS include swallowing and feeding difficulties, poor weight gain and physical growth retardation, recurrent infections such as otitis and pneumonia, orthopedic deformities including scoliosis, and involvement of the CNS (hyperacusis and abnormalities involving the brainstem and cerebellar hypoplasia) [5,22]. Seizures have been reported in up to 10% of patients [22][23][24]. Preoperative management includes ensuring therapeutic anticonvulsant levels prior to the surgical procedure.…”

“…Joint and soft tissue contractures may lead to problems with intraoperative positioning [ 10 , 15 , 24 ]. Growth retardation, nutritional issues, and CNS disabilities may predispose to temperature instability with hypothermia.…”

Anesthesia in Cri du Chat syndrome: Information on 51 Italian patients

“…In addition, many specific abnormalities of the epiglottis have been described: long, curved and floppy [Miyake et al, ]; small and flaccid [Colover et al, ], hypoplasic and hypotonic [Colover et al, ; Taniguchi et al, ]. A pub‐med search (June 2014, key words “cri du chat,” “5p‐,” “anesthesia”) yielded only 10 results, all as case reports or small (three cases) series of patients [Colover et al, ; Taniguchi et al, ; Miyake et al, ; Yamashita et al, ; Himuro et al, ; Castresana et al, ; Brislin et al, ; dos Santos et al, ; Insoo et al, ]; as a total data on 12 patients are available.…”