Angioleiomyoma (Vascular Leiomyoma) of the Oral Cavity

Rawal, Swati Y.; Rawal, Yeshwant B.

doi:10.1007/s12105-017-0827-9

Cited by 14 publications

(12 citation statements)

References 14 publications

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“…According to the exclusion criteria, we selected 30 studies [ 3 , 4 , 8 – 34 ] that included 63 cases of AL. We analyzed patient's age, gender, tumor location, size, and immunohistochemical markers.…”

Section: Review Of the Literaturementioning

confidence: 99%

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Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient

Giudice

Bennardo

Buffone

et al. 2019

Case Reports in Dentistry

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Angioleiomyoma (AL) is an uncommon benign soft tissue neoplasia arising from the tunica media of the smooth muscle cells. AL appears as a solitary and slow-growing mass and seldom is observed in oral tissues. We reported a rare case of AL involving the cheek of a 17-year-old young woman. A review of the English-language literature was performed entering the keywords “angioleiomyoma” and “oral” in the search fields of PubMed. 70 results were identified. Excluded were cases that were not in the oral cavity or not compatible with the AL diagnosis or report lacking immunohistochemical analysis. According to the exclusion criteria, we selected 30 studies that included 63 cases of AL. The results of the review showed an average age of 42.97 years with a prevalence between the fourth and fifth decade of life with a male-to-female ratio of 1.95 : 1. The most affected sites were palate, buccal mucosa of the cheek, lip, tongue, and gingiva. Surgical excision was the treatment of choice, and diagnosis was possible through histopathological and immunohistochemical analysis. SMA, vimentin, CD34, desmin, and S-100 were the most common markers to guide the histopathological diagnosis of oral AL. In conclusion, oral AL is a rare entity, especially in adolescence as in the reported case of AL of the cheek in a 17-year-old woman. The clinical aspects of AL did not allow clinicians to make a correct presumptive diagnosis. A scrupulous histopathological analysis and immunohistochemical examinations are fundamental to differentiate AL from other lesions.

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Section: Review Of the Literaturementioning

confidence: 99%

“…The clinical aspects of AL are similar to many other lesions of the oral cavity. Therefore, the differential diagnosis of AL in the oral cavity includes other benign conditions of the salivary glands as mucocele, pleomorphic adenoma, mesenchymal tumors, lymphangioma, pyogenic granuloma, and schwannoma [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient

Giudice

Bennardo

Buffone

et al. 2019

Case Reports in Dentistry

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“…The treatment of choice for VL is complete surgical excision, with an excellent prognosis and few recurrences have been reported (3). Despite vascular involvement, excessive bleeding during surgery is not commonly observed (12).…”

Section: Discussionmentioning

confidence: 99%

Vascular leiomyoma in the oral cavity – Report of two cases

et al. 2019

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Vascular leiomyomas (VL) are benign lesions of perivascular origin. We report two new cases and discuss their clinical, histological and immunohistochemical characteristics, in order to facilitate the diagnosis and treatment of such lesions. The patients, both male, presented asymptomatic nodules located in the bottom of the labial sulcus and buccal mucosa. In the second case, color doppler ultrasonography was performed, which showed no change in blood flow. After excisional biopsies, a limited lesion was observed histologically, with multiple tortuous vessels of varying sizes and calibers, and among them, spindle cells bundles, positive for smooth muscle actin. Oral VLs have clinical features similar to those of other more common lesions, making preoperative diagnosis difficult. Imaging examination, such as color doppler ultrasonography, may help in diagnosis. In general, excisional biopsy is performed, due to the ease of removal of the lesion during surgery. The treatment of choice is the complete excision of the lesion, which has an excellent prognosis and a low rate of recurrence. Key words: Vascular leiomyoma, spindle cells, thrombus, Doppler.

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“…Leiomyomas are benign mesenchymal tumors arising from nonepithelial tissues, such as smooth muscle [1,2]. These tumors are well-circumscribed neoplasms that are encountered frequently in the dermis, the gastrointestinal tract, and the female genital tract, in particular, the uterus [3,4].…”

Section: Introductionmentioning

confidence: 99%

Leiomyoma of the Cheek

Fonseca

Ramos²,

Baruchi

et al. 2020

Case Reports in Pathology

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Leiomyomas are rare benign tumors that grow in the tunica media of smooth muscle cells. Leiomyomas occur most frequently in the uterus or gastrointestinal tract and only very rarely in the area of the cheek. This study reports on a rare case of a leiomyoma in the cheek of a 43-year-old woman, who presented with a well-circumscribed, asymptomatic, mobile swelling in the right cheek. This swelling was slightly purplish in color and measured approximately 4 cm×3 cm. Surgical excision was the treatment of choice, and the diagnosis was based on histopathological and immunohistochemical stains, which were positive for actin and desmin and negative for AE1/AE3, CD34, and S100. The patient’s follow-up, two years later, showed no recurrence, and she has been asymptomatic since the surgery.

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Angioleiomyoma (Vascular Leiomyoma) of the Oral Cavity

Cited by 14 publications

References 14 publications

Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient

Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient

Vascular leiomyoma in the oral cavity – Report of two cases

Leiomyoma of the Cheek

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