Angiomyofibroblastoma Presenting as Labia Minora Cyst

Abstract

Angiomyofibroblastoma (AMF) is an uncommon soft tissue tumor which occurs principally but not exclusively in the vulvovaginal region of women in their reproductive years. Rarely, in males, the tumor may occur in the scrotum or par testicular tissues with the age ranging from 40 to 80 years. AMF has a diverse histologic and immune histochemical profile. It is a circumscribed edematous slow-growing mesenchymal tumor. Our case report presents a 25-year-old female with a cystic lesion over the labia minor, which was clinically mistaken to be a Bartholin's cyst. In general, AMF is benign, with no local recurrence or metastasis. Hence, wide surgical excision is the sufficient treatment modality. We have also discussed the possible differential diagnosis and their differentiating features on the basis of histology and immune histochemistry.

Angiomyofibroblastoma as a rare cause of vulvar mass: A case report and literature review

“…Regarding the unknown and different characteristics of vulvar AMF, opinions, and clinical approaches are controversial. For instance, Akhtar et al presented a 25‐year‐old woman with a 1.5–2 cm, painless, cystic lesion over the labia minor that was initially thought to be a Bartholin's cyst which has gradually grown in size in the past 2 months 27 . Alves Ruas et al described a 35‐year‐old woman who had painful vulvar swelling with a 7 cm mass in the right labia major for 4 months 28 .…”

“…For instance, Akhtar et al presented a 25‐year‐old woman with a 1.5–2 cm, painless, cystic lesion over the labia minor that was initially thought to be a Bartholin's cyst which has gradually grown in size in the past 2 months. 27 Alves Ruas et al described a 35‐year‐old woman who had painful vulvar swelling with a 7 cm mass in the right labia major for 4 months. 28 Medical history in the cases mentioned above was not significant.…”