Angiotensin II – AT1 receptor antagonists: Design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives

Catalytic role of sodium dodecyl sulfate: Selective synthesis of 1, 2-disubstituted benzimidazoles in water

“…They are important intermediates in many organic reactions [6,7] and act as ligands to transition metals for modelling biological systems [8,9]. In addition, the treatment potency of benzimidazoles in diseases such as ischemia-reperfusion injury [10], hypertension [11], obesity [12] etc. have been recently reported.…”

Polyethylene glycol (PEG-400): An efficient medium for the synthesis of 1,2-disubstituted benzimidazoles

“…ischemia-reperfusion injury (Ogino et al, 2008), hypertension (Shah, Sharma, Bansal, Bansal, & Singh, 2008), obesity (Ghosh & Mandal, 2011), etc. has been recently reported.…”

Benzimidazole: a medicinally important heterocyclic moiety

“…by 36.2 ± 1.9 mm of Hg. They further suggested that pharmacological activities were inversely related to the size of alkyl and aryl substituents (Shah et al, 2008).…”