Purpose To assess the relationship between glaucoma and mortality in a population-based setting. Methods At baseline in 2001, the Beijing Eye Study examined 4356 subjects for glaucoma with a detected glaucoma frequency of 135/ 4356 or 3.1%. Mean age was 55.9 ± 10.4 years (40-101 years). In 2006, all study participants were reinvited for a follow-up examination. Results Out of the 4356 subjects, 3208 (73.6%) subjects returned for follow-up examination, while 124 (2.8%) subjects were dead, and 1024 (23.5%) subjects did not agree to be reexamined or had moved away. 26, 4.20). If the whole glaucoma group was differentiated into an open-angle glaucoma group and an angleclosure group, mortality was still significantly associated with age (Po0.001), gender (Po0.001), level of education (Po0.001), and with the presence of angle-closure glaucoma (P ¼ 0.006; OR: 3.09; 95% CI: 1.49, 10.2), while the association with the presence of openangle glaucoma was marginally significant (P ¼ 0.13; OR: 1.83; 95% CI: 0.84, 4.01). Conclusions The data suggest that glaucoma, particularly angle-closure glaucoma, may be associated with an increased rate of mortality in adult Chinese in Greater Beijing.