Angular domain imaging for tissue mapping

Subsurface Bioimaging using Angular Domain Optical Backscattering Illumination

“…The basic steps of the collimator microfabrication are shown in detail in [1,10]. These collimators started with a furnace <100> silicon wafer oxidation (0.5 μm thick) which is then photolithographicly patterned and etched with HF to create the masking layer of the collimator grooves (see Figure 2).…”

“…Hence, in transillumination ADI only the ballistic and quasiballistic photons will be detected. this technique greatly enhanced detection competing with existing optical imaging methods but with a much simpler detection system [1,10].…”

“…This places a limit on their usage, particularly in the cases of pregnant women and children. In contrast, optical imaging, ultrasound and MR imaging do not carry these risks [1].…”

“…As a result, it is challenging for purely optical imaging to achieve clinically feasible imaging resolution. In our previous works [1,10], Angular Domain Imaging (ADI) tomography was introduced as an optical imaging modality. In this paper we investigate the use ADI with illumination of scattering media on the same side as the detector.…”

“…These angular filters are micromachined silicon collimator channels in microns range wide by with longer length to gain high aspect ratio, giving a tiny acceptance angle behind a CMOS detector array as shown in Figure 1 [1,10]. This method of optical imaging is the one upon which the proposed method of this research is based as explained in the next section.…”