The non-crystalline chalcogenides are solids without long-range order and, as a consequence, they are intrinsically metastable. They exhibit properties different from their crystalline counterparts. The structure and bond configuration of these disordered materials can be changed, sometimes reversibly, either by thermal treatment or by various external factors: light and other electromagnetic radiation, particle beams (electrons, neutrons...), electrical and magnetic fields, pressure, etc. The structure and properties of the glassy or amorphous chalcogenides can be, thus, modified.