Ankle Kinematics and Temporal Gait Characteristics over the Duration of a 6-Minute Walk Test in People with Multiple Sclerosis Who Experience Foot Drop

Linden, Marietta L van der; Andreopoulou, Georgia; Scopes, Judy; Hooper, Julie; Mercer, Thomas H.

doi:10.1155/2018/1260852

Cited by 11 publications

(8 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…71 This is in line with previous studies describing a reduced ankle push off power for forward propulsion, which consequently decreases walking speed. 72 The inability to generate sufficient muscle power for forward propulsion could explain the finding that the majority of the included studies assessing the Cw at slower speeds in pwMS. In addition, since muscle contraction is the main source of energy, the energetic demand increases as a result of muscle co-activation.…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between Walking Speed and the Energetic Cost of Walking in Persons With Multiple Sclerosis and Healthy Controls: A Systematic Review

Theunissen

Plasqui

Boonen

et al. 2021

Neurorehabil Neural Repair

View full text Add to dashboard Cite

Background Persons with multiple sclerosis (pwMS) experience walking impairments, characterized by decreased walking speeds. In healthy subjects, the self-selected walking speed is the energetically most optimal. In pwMS, the energetically most optimal walking speed remains underexposed. Therefore, this review aimed to determine the relationship between walking speed and energetic cost of walking (Cw) in pwMS, compared with healthy subjects, thereby assessing the walking speed with the lowest energetic cost. As it is unclear whether the Cw in pwMS differs between overground and treadmill walking, as reported in healthy subjects, a second review aim was to compare both conditions. Method PubMed and Web of Science were systematically searched. Studies assessing pwMS, reporting walking speed (converted to meters per second), and reporting oxygen consumption were included. Study quality was assessed with a modified National Heart, Lung and Blood Institute checklist. The relationship between Cw and walking speed was calculated with a second-order polynomial function and compared between groups and conditions. Results Twenty-nine studies were included (n = 1535 pwMS) of which 8 included healthy subjects (n = 179 healthy subjects). PwMS showed a similar energetically most optimal walking speed of 1.44 m/s with a Cw of 0.16, compared with 0.14 mL O2/kg/m in healthy subjects. The most optimal walking speed in treadmill was 1.48 m/s, compared with 1.28 m/s in overground walking with a similar Cw. Conclusion Overall, the Cw is elevated in pwMS but with a similar energetically most optimal walking speed, compared with healthy subjects. Treadmill walking showed a similar most optimal Cw but a higher speed, compared with overground walking.

show abstract

Section: Discussionmentioning

confidence: 99%

The Relationship Between Walking Speed and the Energetic Cost of Walking in Persons With Multiple Sclerosis and Healthy Controls: A Systematic Review

Theunissen

Plasqui

Boonen

et al. 2021

Neurorehabil Neural Repair

View full text Add to dashboard Cite

show abstract

“…AFO users have different ages, anatomy, gender, and lifestyles, and can be found at various stages of the disease or disability. Stroke [ 41 , 42 ], multiple sclerosis [ 43 ], cerebral palsy [ 3 , 44 , 45 ], foot drop [ 2 , 8 , 46 ], Charcot-Marie tooth [ 47 ], neck or spinal cord injury [ 48 ], sciatica [ 44 ], muscular dystrophy [ 49 ], or peroneal nerve injury [ 46 ] are the most common diseases that need an AFO to improve the kinematics and kinetics of the patients. Among the AFO functionality, the patient’s comfort, pain, and disability reduction should be an essential factor to consider.…”

Section: Discussionmentioning

confidence: 99%

A Review of Additive Manufacturing Studies for Producing Customized Ankle-Foot Orthoses

et al. 2022

View full text Add to dashboard Cite

Ankle-foot orthoses (AFO) are prescribed to improve the patient’s quality of life. Supporting weak muscles or restraining spastic muscles leads to smoother and more stable locomotion. Commonly, AFO are made using thermoplastic vacuum forming, which requires a long time for production and has limited design options. Additive manufacturing (AM) can solve this problem, leading to a faster and cheaper solution. This review aimed to investigate what is the state-of-art using AM for AFO. Evaluating the used manufacturing processes, customization steps, mechanical properties, and biomechanical features in humans would provide significant insights for further research. The database searches combined AM and AFO with no year or publication type restrictions. Studies must have examined outcomes on human participants with the orthoses built by AM. Other types of orthotic devices or different manufacturing techniques were excluded. Nineteen studies met the inclusion criteria. As stated by having all studies conducted in the last nine years, this is a very recent domain. Different AM processes have been used, with the majority relying on Fused Deposition Modeling. Overall, the manuscripts’ quality is deficient, which is critical to promoting further studies with higher samples. Except for one paper, AM-printed AFO was comparable or superior to the thermoplastic vacuum forming AFO in mechanical tests, kinematics, kinetics, and participant feedback.

show abstract

“…Lower limb paralysis or weakness leading to ‘foot drop’ is a common gait disturbance in people with upper motor neuron conditions such as Multiple Sclerosis (MS) and stroke [ 1 , 2 ]. Foot drop is commonly characterised by a difficulty lifting the toes (dorsiflex) when walking due to fatigue, muscle weakness, and/or spasticity [ 3 ]. This makes walking very tiring and difficult, with greater likelihood of trips, loss of balance, and falls.…”

Section: Introductionmentioning

confidence: 99%

Development of clinical guidelines for service provision of functional electrical stimulation to support walking: mixed method exploration of stakeholder views

et al. 2021

View full text Add to dashboard Cite

Background Over the past 20 years Functional Electrical Stimulation (FES) has grown in clinical use to support walking in people with lower limb weakness or paralysis due to upper motor neuron lesions. Despite growing consensus regarding its benefits, provision across the UK and internationally is variable. This study aimed to explore stakeholder views relating to the value of a clinical guideline focusing on service provision of FES to support walking, how people might use it and what should be included. Methods A mixed methods exploration sought the views of key stakeholders. A pragmatic online survey (n = 223) focusing on the study aim was developed and distributed to the email distribution list of the UK Association for Chartered Physiotherapists Interested in Neurology (ACPIN). In parallel, a qualitative service evaluation and patient public involvement consultation was conducted. Two group, and seven individual interviews were conducted with: FES-users (n = 6), their family and carers (n = 3), physiotherapists (n = 4), service providers/developers (n = 2), researchers (n = 1) and distributors of FES (n = 1). Descriptive analysis of quantitative data and framework analysis of qualitative data were conducted. Results Support for clinical guideline development was clear in the qualitative interviews and the survey results. Survey respondents most strongly endorsed possible uses of the clinical guideline as ensuring best practice and supporting people seeking access to a FES service. Data analysis and synthesis provided clear areas for inclusion in the clinical guidelines, including current research evidence and consensus relating to who is most likely to benefit and optimal service provision as well as pathways to access this. Specific areas for further investigation were summarised for inclusion in the first stage of a Delphi consensus study. Conclusions Key stakeholders believe in the value of a clinical guideline that focuses on the different stages of service provision for FES to support walking. A Delphi consensus study is being planned based on the findings.

show abstract

Ankle Kinematics and Temporal Gait Characteristics over the Duration of a 6-Minute Walk Test in People with Multiple Sclerosis Who Experience Foot Drop

Cited by 11 publications

References 29 publications

The Relationship Between Walking Speed and the Energetic Cost of Walking in Persons With Multiple Sclerosis and Healthy Controls: A Systematic Review

The Relationship Between Walking Speed and the Energetic Cost of Walking in Persons With Multiple Sclerosis and Healthy Controls: A Systematic Review

A Review of Additive Manufacturing Studies for Producing Customized Ankle-Foot Orthoses

Development of clinical guidelines for service provision of functional electrical stimulation to support walking: mixed method exploration of stakeholder views

Contact Info

Product

Resources

About