Annulation strategies for diverse heterocycles via the reductive transformation of 2-nitrostyrenes

Abstract

Reduction of the stable nitro group is a fundamental and widely used transformation for the construction of complex and functionalized heterocyclic architectures. The unfolding of the reactivity of the nitro...

Developments and applications of α-bromonitrostyrenes in organic syntheses

“…20,21 Recently, progress in asymmetric domino reactions utilizing chiral organocatalysts has been well revealed and interesting achievements has been gained. [22][23][24] Recently, various research teams, such as Jakubec, 25 Gao, 26 Lee, 27 Halimehjani, 28 Shen, 29 and Zhang 30 reported the organic transformations of nitrostyrenes. In this review, we have specically discussed the use of a-bromonitrostyrenes in various types of catalytic systems, such as organocatalysis, metal catalysis and base catalysis as well as catalyst-free reactions.…”

Three‐Component Synthesis of Thiazole‐2‐thione from Chalcone, Nitrobenzene and Carbon Disulfide

“…[13] Meanwhile, nitrobenzene is the main raw material for building heterocyclic compounds, especially for nitrogen-containing and sulfurcontaining heterocycles. [14] For example, in 2017, Nguyen's group developed a redox-neutral method to access sulfonamides from 2-nitrochalcones and elemental sulfur (Scheme 1, b). [15] Additionally, in 2019, we developed an iron-promoted three-component procedure for the preparation of benzothiazoles via nitroarene ortho-CÀ H sulfuration with elemental sulfur (Scheme 1, c).…”