Another Etiological Factor of Meibomian Gland Loss in Patients with Polycystic Ovary Syndrome: Inflammation

Acet, Yakup; Sarikaya, Sevcan

doi:10.1089/jop.2022.0097

Cited by 5 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acetand Sarikaya similarly concluded that inflammation might contribute to meibomian gland loss in individuals with Polycystic Ovary Syndrome (PCOS). Contrarily, they found no significant impact of inflammation on tear film instability parameters in the same study ( 21 ). Another recent Turkish study demonstrated that inflammatory parameters in acne patients did not significantly affect tear film stability and meibomian gland loss ( 22 ).…”

Section: Discussionmentioning

confidence: 81%

“…Another recent Turkish study demonstrated that inflammatory parameters in acne patients did not significantly affect tear film stability and meibomian gland loss ( 22 ). The divergent results observed in PCOS and acne patients in these two studies, despite similar methodologies, underscore the noteworthy variations in the active roles of inflammation parameters across distinct diseases ( 21 , 22 ).…”

Section: Discussionmentioning

confidence: 83%

See 1 more Smart Citation

The Role of Systemic Inflammation in Acquired Nasolacrimal Duct Obstruction

Dag

2023

Beyoglu Eye J

View full text Add to dashboard Cite

Objectives: This study aims to investigate the influence of systemic inflammation on adult patients with acquired nasolacrimal duct obstruction (ANLDO). Methods: Peripheral venous blood analysis was performed on adult patients who underwent dacryocystorhinostomy for ANLDO between June 2020 and December 2022, during their remission period just before the surgery. Platelet, Neutrophil, Lymphocyte, Monocyte, White Blood Cell (WBC) count, Platelet/Lymphocyte ratio (PLR), Neutrophil/Lymphocyte ratio (NLR), Monocyte/Lymphocyte ratio (MLR), and systemic inflammatory index (SII) (calculated as platelet × (neutrophil/lymphocyte)) were compared with a volunteer control group. Results: The study included 54 adult patients with ANLDO and 54 individuals in the control group. The mean age was 42.5±14.4 years in the ANLDO group and 37.8±12.3 years in the volunteer control group. There was no significant difference in age between the groups (p=0.064). Platelet value (295.9±70.9→254.7±43.9), PLR value (143.8±77.7→119.0±36.1), and SII value (534.7±192.0→442.6±212.2) in the ANLDO group were significantly higher compared to the Control group (p=0.000, p=0.023, p=0.020, respectively). Neutrophil, lymphocyte, monocyte, NLR, MLR, and WBC values did not exhibit significant differences between the case and control groups (p=0.299, p=0.469, p=0.125, p=0.419, p=0.143, and p=0.465, respectively). Conclusion: The study revealed elevated systemic platelet counts in ANLDO patients, resulting in higher PLR and SII values. The authors suggest that a histopathological examination to assess the local impact of platelets or other inflammatory processes in nasolacrimal duct obstruction could offer valuable insights into the etiopathology of ANLDO.

show abstract

Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 83%

The Role of Systemic Inflammation in Acquired Nasolacrimal Duct Obstruction

Dag

2023

Beyoglu Eye J

View full text Add to dashboard Cite

show abstract

“…We compared these values between the groups. The device software also provides qualitative values, such as each breakup's localization [ 7 , 32 , 33 ]. After taking the participants’ NI-BUT measurements, we performed detailed slit-lamp and funduscopic examinations of all participants.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of the Effect of İnfection and İmmunity on the Tear Film by Scheimpflug-Placido Disc Topography- A Case Control Study

DAĞ

Acet

2023

Photodiagnosis and Photodynamic Therapy

Self Cite

View full text Add to dashboard Cite

“…5,6 As is the case with other sebaceous glands, MGs, as a modified sebaceous gland, is affected by hormonal and/or inflammatory changes. [7][8][9][10][11] In our previous study, we found decreased tear film stability and accompanying increased MG loss in patients with AV. 11 Muhafiz et al found that the tear film pattern was more disturbed and MG losses was higher in patients with AV.…”

mentioning

confidence: 99%

“…They conclude that inflammation may be the etiological factor for MG loss in patients with polycystic ovary syndrome. 7 In the present study, tear film stability and MG loss in patients with AV were analyzed and the extent of the effect of inflammatory processes on a possible MG and/or tear film disorder in AV patients was examined. Accordingly, the correlation between tear film parameters and MG loss rates with the rates of peripheral blood values were investigated in patients with AV.…”

mentioning

confidence: 99%

The Role of Inflammation in Meibomian Gland Loss and Tear Film Instability in Patients with Acne Vulgaris: A Correlation Study

Acet¹,

Dag²

2023

Turkiye Klinikleri J Ophthalmol

View full text Add to dashboard Cite

To examine the relationship of tear film instability and meibomian gland (MG) loss with inflammatory markers in female participants diagnosed with acne vulgaris (AV). Material and Methods: 75 eyes of 75 female participants diagnosed with AV were included in the study. All participants consist of patients who applied to the dermatology outpatient clinic and will be treated with isotretinoin. MG losses in meibography were examined. The correlation between the participants' NI-BUT parameters and the amount of MG loss with the Systemic Immune-Inflammation Index (SII), which is the value obtained from the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and platelet count×(NLR) was examined. Results: The mean age of the participants was 24.7±5 year. Mean NI first -BUT value was found to be 4.8±3.4 sec. Mean NI average -BUT value was found to be 7.4±3.1 sec. MG loss in the upper lid was found to be 37.4%±14.6%. The rate of MG loss in the lower lid was found to be 48.0 %±15.9%. There was no significant correlation between NI first -BUT and NI average -BUT value and NLR, PLR and SII (p>0.05). There was no significant correlation between upper& lower lid MG loss rate and NLR, PLR and SII (p>0.05). Conclusion: We observed that noninvasive tear break-up time parameters and MG loss were not correlated with inflammatory markers in patients with AV. We think that factors other than inflammatory parameters should be investigated as the etiological factor of MG loss and tear film instability in patients with AV.

show abstract

Another Etiological Factor of Meibomian Gland Loss in Patients with Polycystic Ovary Syndrome: Inflammation

Cited by 5 publications

References 32 publications

The Role of Systemic Inflammation in Acquired Nasolacrimal Duct Obstruction

The Role of Systemic Inflammation in Acquired Nasolacrimal Duct Obstruction

Evaluation of the Effect of İnfection and İmmunity on the Tear Film by Scheimpflug-Placido Disc Topography- A Case Control Study

The Role of Inflammation in Meibomian Gland Loss and Tear Film Instability in Patients with Acne Vulgaris: A Correlation Study

Contact Info

Product

Resources

About