Anterior Radiculopathy and Lupus Erythematosus Cells: Report of Case

Systemic Lupus Erythematosus Presenting with Recurrent Acute Demyelinating Polyneuropathy

“…Early neuropsychiatrie features usually include sei zures, myelitis and chorea [4], It is accepted that peripheral neuropathy of a variety of types occurs in SLE. Over the years, several reports of moderately severe, predominantly motor polyneuropathy associated with total areflexia and a protein cytologic dissociation in the CSF have appeared [6,7,[9][10][11][12][13]. All of these patients have been women.…”

“…2 of Rechtland et al [6] and the case of Gargour ct al. [7] have cither had clinical signs and symptoms of SLE before the onset of neuropathy or developed such symptoms simultaneously with the neuropathy. Also, with the excep tion of the recent report by Rechtland et al [6], none had elcctrodiagnostic studies or morphological studies using special tech niques such as leased fiber preparations that would indicate a primary demyelinating neu ropathy.…”

“…Gargour et al [7] reported a patient with more than a 3-year history of progressive weakness and areflexia who had no evidence of lupus before or dur ing the course of the neuropathy. The diagno sis of SLE was based on the occurrence of positive LE cells.…”

“…In a significant proportion, the nervous system signs occur early in the disease, and in a small minority they are cither the sole ini tial feature or present simultaneously with other systemic features [2,4], Though a pe ripheral nerve syndrome may occur in up to 12% of the patients [2,3,5], peripheral poly neuropathy as a presenting feature has been distinctly rare [6,7], The peripheral neuropa thy that has been reported with SLE has usually been of a chronic type with the sys temic features of SLE already present or oc curring simultaneously with the neuropathy.…”

Review of American and English literature for the years 1963 and 1964 (Seventeenth Rheumatism Review)

“…NEUROLOGICAL Psychoses and convulsions, presumably on the basis of cerebral vasculitis, were frequent manifestations of SLE (318,417). Other neurological manifestations included cerebrovascular accidents ( 1166), Sydenham's chorea (193) and peripheral neuritis (318,424).…”