Anthelmintic resistance in sheep and goat farms on Peninsular Malaysia

Chandrawathani, P; Adnan, M; Waller, P.J.

doi:10.1016/s0304-4017(99)00028-x

Cited by 59 publications

(34 citation statements)

References 8 publications

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“…e Trichostrongylus sp., nas coproculturas, foi semelhante, ao relatado por Vieira et al (2008) e Pereira et al (2008, em municípios do Rio Grande do Sul; assim como na revisão realizada por Farias et al (1997), considerando estudos realizados na região Sul do Brasil. Chandrawathani et al (1999) A maior prevalência de Strongyloides sp., relatada para o rebanho identificado como Angélica (Quadro 1), possivelmente ocorreu devido a presença de animais jovens nos grupos experimentais. Entretanto, Ahid et al (2008), no Rio Grande do Norte, identificaram 52,3% das larvas infectantes como pertencentes ao mesmo gênero, e relataram não ter encontrado diferenças quanto a percentagem de Strongyloides sp.…”

Section: Discussionunclassified

“…Outros estudos revelam índices de resistência mais baixos (Melo et al 2003, Álvarez-Sánchez et al 2006, Traversa et al 2007, Köse et al 2007); mas considerando a situação desse fenômeno no mundo, é possível dizer que existe tendên-cia de aumento nos níveis de resistência pela persistên-cia do uso desta base, em virtude da cultura dos criadores em atribuir a ela alta eficiência facilitada pela redução do preço dessa formulação. A formulação contendo Closantel apresentou alto ín-dice de resistência anti-helmíntica nos rebanhos testados, semelhante ao descrito por Soccol et al (1996) e Chandrawathani et al (1999). Mas oposto ao relatado por Echevarria et al (1996), onde cerca de 80,5% das propriedades testadas foram consideradas portadoras de isolados de helmintos sensíveis a essa molécula.…”

Section: Discussionunclassified

“…Buzzulini et al (2007), também testaram essa molécula, na forma injetável e não obtiveram reduções satisfatórias na contagem de OPG. Chandrawathani et al (1999) relataram apenas suspeita de resistência anti-helmíntica à Moxidectina, em 38% dos rebanhos estudados. Resultados distintos do relatado por Traversa et al (2007), em que observaram redução de 100% da contagem de OPG em todos os rebanhos onde a molécula foi utilizada.…”

Section: Quadro 4 Percentuais Da Condição De Resistência (R) Baixa unclassified

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Resistência anti-helmíntica de nematóides gastrintestinais em ovinos, Mato Grosso do Sul

Sczesny-Moraes

Bianchin²,

Silva³

et al. 2010

Pesq. Vet. Bras.

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ABSTRACT.-Sczesny-Moraes E.A., Bianchin I., Silva K.F., Catto J. Among the methods of control of gastrointestinal worms in sheep, the use of chemicals is the most common. However, the continued, and indiscriminate, use of these products has selected populations of resistant helminths to anthelmintics, a phenomenon reported in the whole world. This study aimed to identify the species of gastrointestinal parasites and diagnose the status of anthelmintic resistance in sheep in the State of Mato Grosso do Sul Brazil. Feacal egg count reduction tests (FECRT) were performed in flocks of sixteen farms, and the seven formulations used contained the following pharmacological bases: Albendazole, Ivermectin, Levamizol, Trichlorfon, Moxidectin, Closantel and one containing the first three in association. The species identified at necropsy, in adult sheep, were: Haemonchus contortus, Trichostrongylus colubriformis, Cooperia curticei, C. punctata, C. pectinata and Oesophagostomum columbianum, in order of prevalence. The formulations containing Albendazole and Ivermectin did not show efficacy in reducing the EPG in the flocks tested, with average reductions of 0.7 and -19.6%, respectively. Closantel presented an average efficacy of 6.7%; Levamisolee, Moxidectin and Trichlorfon, 28.7, 26.8 and 65% respectively, the combination of three bases (Albendazole, Ivermectin and Levamizol), an average efficacy of 55.8 %. The average percentages of infective larvae recovered in the faecal cultures, pre and post treatment were similar, indicating that resistance to the bases tested is present in all species cited, to a greater or lesser degree. The two genera predominantly resistant are Haemonchus sp., with 86.9%, followed by Trichostrongylus sp., with an average of 47.5%, Strongyloides sp. 33.6%, Oesophagostomum sp.

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Section: Discussionunclassified

Section: Quadro 4 Percentuais Da Condição De Resistência (R) Baixa unclassified

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Resistência anti-helmíntica de nematóides gastrintestinais em ovinos, Mato Grosso do Sul

Sczesny-Moraes

Bianchin²,

Silva³

et al. 2010

Pesq. Vet. Bras.

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“…The LD 50 was higher than 0.1mg/ml thiabendazole indicating resistance, which in agreement to the present study. The economic significance of helminths throughout the World [40] necessitates immediate attention to launching an effective control program. Chemical control is the main part of all helminth control programs [22] .…”

Section: Discussionmentioning

confidence: 99%

Pakistan’ın Kuzey Punjab Eyaletindeki Koyun ve Keçilerde Haemonchus contortus ve Teladorsagia circumcincta’nın Anthelmentiklere Karşı Direncinin Belirlenmesi

Muhammad¹,

Ahmed²,

Iqbal³

et al. 2015

Kafkas Univ Vet Fak Derg

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The present study was conducted to investigate the efficacy of albendazole, levamisole and ivermectin against gastrointestinal nematodes of sheep and goats. One hundred and sixty small ruminants comprised four breeds, sheep (Salt range and Pak Karakul) and goats (Jattal and Beetal) were selected for this experiment. These animals were artificially infected with nematodes (Haemonchus contortus and Teladorsagia circumcincta). FECs were done to confirm the presence of adult stages of H. contortus and T. circumcincta. The selected sheep and goat were divided into four groups. First group was treated with albendazole, second with levamisole, third with ivermectin and fourth kept as untreated to serve as control. Faecal samples were collected on day first prior to administration of treatment followed by day 14 post treatment. The efficacy of each anthelmintic was measured using the faecal egg count reduction test and egg hatch test. The percentage reduction in FECs (95% CI) for albendazole, levamisole and ivermectin for salt range sheep were 88%, 89% and 99%, for Pak karakul sheep, 91%, 90% and 97%, for Jattal goat 91%, 91% and 98%, and for Beetal goat 91%, 92% and 99%. All results showed the presence of multiple anthelmintic resistances in selected sheep and goats flocks. All flocks were found resistance against the albendazol and three were resistance against levamisole. The arithmetic faecal egg count reduction with albendazole, levamisole and ivermectin recorded for H. contortus and T. circumcincta indicated the resistance against albendazole and levamisole and susceptibility of these worms against ivermectin. The results revealed that a significant difference (P<0.05) of FECRT were found on pre-treatment and post-treatment with different anthelmintic drug as compared to control group in all the flocks. The results of egg hatch test indicated that LC 50 were ranged from 0.138 µg/mL to 0.141 µg/mL for four breeds, which were more than 0.1ug/ml of albendazole. Result indicates that resistance was found in the eggs with albendazole. The egg hatch assay also confirmed the result of faecal egg count reduction test. gününde dışkı örnekleri toplandı. Herbir anthelmentiğin etkinliği dışkı yumurta sayımı azalma testi ve yumurta açılımı testi ile belirlendi. Albendazol, levamizol ve ivermektin için dışkı yumurta sayımında % azalma Salt range koyununda sırasıyla %88, %89 ve %99, Pak karakul koyununda %91, %90 ve %97, Jattal keçisinde %91, %91 ve %98, ve Beetal keçisinde %91, %92 ve %99 olarak tespit edildi. Çalışmanın sonuçları seçilen koyun ve keçi sürülerinde anthelmentik direncin mevcut olduğunu göstermiştir. Tüm sürüler albendazola karşı dirençli bulunurken üçü levamizole karşı dirençliydi. H. contortus ve T. circumcincta için albendazol, levamizol ve ivermektin ile tespit edilen aritmetik dışkı yumurta sayımı azalma albendazol ve levamizole karşı direnci gösterirken ivermektine karşı duyarlılığı ortaya koymuştur. Tüm sürülerde kontrol grubu ile karşılaştırıldığında uygulama öncesi ve sonrası arasında dışkı yumur...

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“…Over the past five decades, the control of this parasite has been achieved mainly through intensive chemo prophylaxis based on the repeated use of anthelmintic drugs (Mohammed et al, 2013). The emergence of nematode population resistant to one or more of the currently available broad spectrum anthelmintics is a worldwide phenomenon and is particularly severe in small ruminants (Chandrawathani et al, 1999;Leethwick et al, 2001;Ombasa et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Anthelmintic Activity of Plants Especially of Aristolochia Species in Haemonchosis: A Review

Mini¹,

Venkateswa²,

Gomathinay³

et al. 2015

Asian J. of Animal and Veterinary Advances

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Haemonchosis is one of the common helminthic diseases of ruminants which causes high mortality. Course of infection depends on the worm burden, age and nutrition of the host. The principal feature of Haemonchus species infection is anaemia. Anthelmintics with different modes of action are the necessity of the hour, which has changed the focus to other sources like plants. Screening of medicinal plants for their anthelmintic activity has become great scientific interest. Ethnopharmacological surveys provide the rationale for selection and scientific investigation of medicinal plants. Herbal drugs are extensively used as anthelmintics in the developed world before the era of broad spectrum drugs. Many currently available therapeutic compounds are plant derived or synthetic analogues derived from those compounds. Plants of the genus Artemisia were used against the nematodes Ascaris suum and Toxocara spp. as well as cestodes of poultry. From time immemorial, plant derivatives like Nicotiana tabaccum have been used against Moneizia, Ascaridia and several species of GI nematodes including Cooperia, Haemonchus, Nematodirus and Trichostrongylus. Arecoline and several other alkaloids from the dried ripe seeds of Areca catechu were found to be active against tapeworms in dogs and poultry. Aristolochia species of plant are traditionally used for neatodiasis in India. In this review an effort is made to compile the available reports and studies about the anthelmintic activity and use of different plants especially of Aristolochia with special reference to Haemonchosis.

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Anthelmintic resistance in sheep and goat farms on Peninsular Malaysia

Cited by 59 publications

References 8 publications

Resistência anti-helmíntica de nematóides gastrintestinais em ovinos, Mato Grosso do Sul

Resistência anti-helmíntica de nematóides gastrintestinais em ovinos, Mato Grosso do Sul

Pakistan’ın Kuzey Punjab Eyaletindeki Koyun ve Keçilerde Haemonchus contortus ve Teladorsagia circumcincta’nın Anthelmentiklere Karşı Direncinin Belirlenmesi

Anthelmintic Activity of Plants Especially of Aristolochia Species in Haemonchosis: A Review

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