“…Physiologically, the metabolic oxygen demand of aerobic organisms rises with increasing temperature (Pörtner & Knust, 2007), such that deoxygenation has greater impacts on organismal growth and survival under high temperature conditions (Deutsch et al, 2015; Deutsch et al, 2020). At the same time, higher temperature favors oxygen loss by decreasing seawater oxygen solubility and increasing stratification, which limits the ventilation rate of thermocline water masses (Franco et al, 2021; Kwon et al, 2016; Ono et al, 2001; Sasano et al, 2018). Among all oceanic regions, the Northeast Pacific exhibits one of the most rapid apparent rates of deoxygenation (Keeling et al, 2010; Schmidtko et al, 2017), with large oxygen decreases projected for intermediate depths over the coming decades (Long et al, 2016).…”